BACKGROUND Although exercise-induced ST depression is an independent predictor of future coronary events in asymptomatic populations, the predictive value of ST depression beginning after exercise cessation is unknown. METHODS AND RESULTS We analyzed the treadmill exercise tests of 825 healthy volunteers who were 22 to 89 years of age from the Baltimore Longitudinal Study of Aging. All subjec...

BACKGROUND Isolated ST elevation in lead aVR in combination with global ST depression with normalization after rehydration is a unique electrocardiographic pattern that is associated with a broad range of diagnoses. Its association with left main coronary artery disease and other acute coronary syndromes suggest the need for early and aggressive cardiac evaluation. CASE REPORT A 53-year-old man...

ST segment depression and T waves inversion are electrocardiographic (ECG) repolarization abnormalities often encountered in clinical medical practice that have been proved to predict future cardiovascular events. We present the case of a 62-year-old male patient, asymptomatic, with ST segment depression and inverted T waves discovered incidentally on resting ECG. Echocardiographic and laborato...

Coronary spasm is an accepted cause of transient myocardial ischemia in patients with variant angina; more recently it has been suggested that dynamic stenoses could also play an important role in the pathophysiology of exertional angina. To test this hypothesis we submitted 31 patients with histories typical of exertional angina to ergonovine testing and compared the electrocardiographic and c...

Over 25% of adult Americans suffer from a mental disorder each year, with depression and anxiety being some of the most commonly reported issues. Researchers estimate that between 10% and 50% of adult Americans will suffer from a depressive episode at some point in their life, and cognitive theorists argue that mental states, including disorders, are generated and maintained by personal, subjec...

A randomised double blind study was carried out with 50 men who had ST segment depression of 0.1 mV or more after a modified two-step exercise test. Rate and duration of exercise were the same for the last of each subject's several pretreatment tests as for his tests after 4 and 8 weeks of treatment with placebo or testosterone cypionate, 200 mg, intramuscularly weekly. The sum of ST segment d...

The ST-segment response during maximal treadmill exercise was quantitated by digital computer after excessive noise in the electrocardiographic data was reduced by computer averaging. Both the slope and the depression were quantitated. Two groups of subjects were studied. Group A consisted of 35 subjects between 33 and 57 years of age with confirmed or suspected coronary artery disease. Group N...

The sensitivity of myocardial perfusion imaging (MPI) using thallium-201 injected both at rest and during peak exercise was compared to simultaneously recorded 12 lead electrocardiography (ECG) for the detection of transient ischemia in 20 normal subjects and 63 patients with coronary artery disease (CAD). No significant perfusion defects or ECG changes were seen on either the rest or exercise ...

The aim of the present study was to assess the long-term clinical course of patients with syndrome X, focusing on different courses between exercise-induced ST depression and chest pain. Forty-three patients with syndrome X were followed up for 6.4 +/- 3.8 years. They were divided into the 3 groups according to chest pain: disappeared (n = 24), improved (n = 14), or unchanged (n = 5). No patien...

The ST-segment response during maximal treadmill exercise was quantitated by digital computer after excessive noise in the electrocardiographic data was reduced by computer averaging. Both the slope and the depression were quantitated. Two groups of subjects were studied. Group A consisted of 35 subjects between 33 and 57 years of age with confirmed or suspected coronary artery disease. Group N...