M ultiple, large randomised trials comparing primary percutaneous coronary intervention (PCI) with fibrinolytic therapy for ST elevation myocardial infarction (STEMI) have shown that primary PCI results in lower rates of death, reinfarction, and stroke. Consequently, primary PCI has become the preferred reperfusion strategy for STEMI. Unfortunately, primary PCI is available in only a minority o...

The effect of a history cancer on the prognosis patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) is poorly understood.

Whether reduced-dose prasugrel has a better efficacy or safety than standard-dose clopidogrel remains unknown in patients undergoing percutaneous coronary intervention (PCI).

BACKGROUND Published meta-analyses comparing primary percutaneous coronary intervention with fibrinolytic therapy in patients with ST-segment-elevation myocardial infarction include only randomized controlled trials (RCTs). We aim to obviate the limited applicability of RCTs to real-world settings by undertaking meta-analyses of both RCTs and observational studies. METHODS AND RESULTS We incl...

Primary percutaneous coronary intervention (pPCI) with routine stenting of the culprit lesion has greatly improved short-term and immediate outcomes ST-elevation myocardial infarction (STEMI).

ABSTRACT BACKGROUND Primary percutaneous coronary intervention represents one of the cornerstone management modalities for patients with acute ST-elevation myocardial infarction and has undergone tremendous growth over the past two decades. This study was aimed to determine the early clinical outcomes of primary percutaneous coronary interventions in a tertiary-level teaching hospital withou...

n engl j med 359;7 www.nejm.org august 14, 2008 753 Future PCI/stent use among stable angina patients could 2. depend on COURAGE: managed care first report. (Accessed July 25, 2008, at http://www.mccfirstreport.com/show_story. php?newsid=1172.) Weintraub WS, Spertus JA, Kolm P, et al. Effect of PCI on 3. quality of life in patients with stable coronary disease. N Engl J Med 2008;359:677-87. Spe...

Background Occluded Artery Trial (OAT) demonstrated that percutaneous coronary intervention (PCI) with optimal medical therapy does not reduce the frequency of major adverse events compared to optimal medical therapy alone when performed on days 3-28 post ST-elevation myocardial infarction (STEMI) in stable patients. However the assessment of infarct zone (IZ) viability was not used as an inclu...