There are few reports of the application of antibiosis as a possible means of controlling Verticillium alboatrum Reinke and Berthold. Most of these publications are concerned with in vitro studies which report the effects of various organisms or their products on V. albo-atrum (Ark and Hunt, 1941; Arnstein et al., 1948; Smith, 1947). Wilhelm (1951a) effected a reduction in the inoculum potentia...

The microbial exposure associated with health complaints in moldy houses consists of a heterogeneous group of components, including both living and dead bacteria, fungi, and their metabolites and active compounds. However, little is known about the interactions between different microbes and their metabolites, although the cytotoxicity and inflammatory potential of certain individual microbes h...

Stachybotrys chartarum is a black mitosporic fungus capable of dense colonization of cellulose-based building materials such as drywall. The presence of S. chartarum in indoor environments has been reported as linked to a variety of alleged environment-related illnesses including infant acute idiopathic pulmonary hemorrhage, although there continues to be insufficient (especially exposure) data...

The fungus Stachybotrys chartarum has been implicated in cases of nonspecific indoor air quality complaints in adults and in cases of pulmonary hemorrhaging in infants. The effects that have been described have been attributed to mycotoxins. Previous dose-effect studies focused on exposure to a single mycotoxin in a solvent, a strategy which is unlikely to accurately characterize the effects of...

BACKGROUND A geographic cluster of 10 cases of pulmonary hemorrhage and hemosiderosis in infants occurred in Cleveland, Ohio, between January 1993 and December 1994. STUDY DESIGN This community-based case-control study tested the hypothesis that the 10 infants with pulmonary hemorrhage and hemosiderosis were more likely to live in homes where Stachybotrys atra was present than were 30 age- an...

OBJECTIVE Despite the growing body of evidence showing adverse health effects from inhalation exposure to the trichothecene-producing mold Stachybotrys chartarum, controversy remains. Currently, there are no reliable assays suitable for clinical diagnosis of exposure. We hypothesized that satratoxin G (SG) -albumin adducts may serve as biomarkers of exposure to this fungus. DESIGN We studied ...