نتایج جستجو برای: stage liver disease

تعداد نتایج: 1997894  

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2017
Robert Schierwagen Frank Erhard Uschner Fernando Magdaleno Sabine Klein Jonel Trebicka

The evolution of chronic liver injuries from benign and manageable dysfunction to life threatening end-stage liver disease with severe complications renders chronic liver disease a global health burden. Because of the lack of effective medication, transplantation remains the only and final curative option for end-stage liver disease. Since the demand for organ transplants by far exceeds the sup...

Journal: :Journal of Cardiothoracic and Vascular Anesthesia 2011

Journal: :The Medical Journal of Cairo University 2018

2017
Diogo Telles-Correia António Barbosa Helena Cortez-Pinto Carlos Campos Nuno B F Rocha Sérgio Machado

The liver is the organ by which the majority of substances are metabolized, including psychotropic drugs. There are several pharmacokinetic changes in end-stage liver disease that can interfere with the metabolization of psychotropic drugs. This fact is particularly true in drugs with extensive first-pass metabolism, highly protein bound drugs and drugs depending on phase I hepatic metabolic re...

Journal: :American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016
J Levitsky J G O'Leary S Asrani P Sharma J Fung A Wiseman C U Niemann

Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated th...

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