Coamorphous formation between the hydrophobic drugs nifedipine (NIF) and ketoconazole (KTZ) was investigated with expectation of improving solubility permeability two compounds. NIF KTZ spray-dried particles (SDPs) were prepared in a range NIF/KTZ molar ratios (3/1-1/3). All SDPs an amorphous state single glass transition temperature (Tg). The Tg value (1/1) showed largest positive deviation fr...

Many medical images suffer from the partial volume effect where a boundary between two structures of interest falls in the midst of a voxel giving a signal value that is a mixture of the two. We propose a method to restore the ideal boundary by splitting a voxel into subvoxels and reapportioning the signal into the subvoxels. Each voxel is divided by nearest neighbor interpolation. The gray lev...

In semidefinite programming (SDP), unlike in linear programming, Farkas’ lemma may fail to prove infeasibility. Here we obtain an exact, short certificate of infeasibility in SDP by an elementary approach: we reformulate any equality constrained semidefinite system using only elementary row operations, and rotations. When a system is infeasible, the reformulated system is trivially infeasible. ...

We tested metrics from full-waveform (FW) LiDAR (light detection and ranging) as predictors for forest basal area (BA) and aboveground biomass (AGB), in a tropical moist forest. Three levels of metrics are tested: (i) peak-level, based on each return echo; (ii) pulse-level, based on the whole return signal from each emitted pulse; and (iii) plot-level, simulating a large footprint LiDAR dataset...

A variety of analysis and design problems in control, communication and information theory, statistics, combinatorial optimization , computational geometry, circuit design, and other elds can be expressed as semideenite programming problems (SDPs) or determinant maximization problems (max-det problems). These problems often have matrix structure, i.e., some of the optimization variables are mat...

a flow injection method is reported for the determination of ascorbic acid based on amperometric detection, using a cobalt(ii) phthalocyanine (copc) modified graphite-epoxy electrode. the amperometric respons was evaluated with regard to ph, ionic strength of the electrolyte, flow rate of the carrier solution, injected sample volume and conditioning time of the electrode. the limit of detection...

We virtually restore faded black and white photographic prints by the method of decomposing the image into a smooth component that contains edges and smoothed homogeneous regions, and a rough component that may include grain noise but also fine detail. The decomposition into smooth and rough components is achieved using a rational filter. Two approaches are considered; in one, the smooth compon...