In a series of 16 oxyphilic follicular neoplasms of the thyroid (8 adenomas and 8 carcinomas), three different approaches for the analysis of morphometric data were evaluated. It was shown that the statistical design of morphometric studies is by nature nested due to subsampling of cells within each patient. Therefore, the most appropriate analysis would be to account for this hierarchical stru...

The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...

The purpose of this study was to determine the effect breaking dormancy and giving bokashi bark leaves on growth salak ( Salacca Sumatrana ) seedlings. This used a factorial randomized block design (RBD) with 3 blocks (replications). For factor is act midrib. statistical results showed that treatment action had significant effect, leaf area plant height, application fertilizer did not show heig...

Green synthesis of silver nanoparticles (AgNPs) involves a reduction reaction metal salt solution mixed with plant extract. The yield can be controlled using several independent factors, such as extract and concentration, temperature, incubation time. AgNPs from Origanum vulgare (oregano) were synthesized in the past. However, no investigations performed on combined effects factors that affect ...

Multi-level factorial designs are useful in experiments but their aliasing structure are complex compare to two-level fractional factorial designs. A new framework is proposed to study the complex aliasing of those designs. Geometric aliasing is deened for factorial designs. It generalize of the aliasing relation of regular two level fractional fac-torial designs to all factorial designs. Based...

Minimum aberration designs are obtained for two types of mixed-level fractional factorial: (i) (s) × s factorial, and (ii) (s1) × (s2) × s factorial, where s is any prime or prime power, and r, r1, r2 and n are positive integers. Projective geometric tools are employed to find the wordlength pattern of a given design in terms of that of its complementary set. Many useful designs are found

Optimization of bacteriocin production by Lactobacillus plantarum LPCO10 was explored by an integral statistical approach. In a prospective series of experiments, glucose and NaCl concentrations in the culture medium, inoculum size, aeration of the culture, and growth temperature were statistically combined using an experimental 2(3)(5-2) fractional factorial two-level design and tested for the...

Many studies have demonstrated the effect of various beverages on hard tissues of the mouth. Sugar consumption has also been avoided because it is associated with caries activity, and artificial sweetener research has been promoted. In this paper, data about the buffer capacity of black tea and yerba mate supplemented with sugar or one of two artificial sweeteners (Barny diet and NutraSweet) we...