نتایج جستجو برای: status of aggregation
تعداد نتایج: 21203500 فیلتر نتایج به سال:
in the present study, an application of multilevel modeling approach to the input- output analysis are presented first, the regional input-output table of all provinces in iran was extracted based on the adjusted flegg location quotient method (aflq). second differentiation in the leontief technical coefficients and the backward and forward linkages among various activities and sectors of all p...
this study aimed to investigate the effects of economic status and level of education on the choice of address terms by iranian couples in shahrekord, iran. to this end, 50 couples were selected, based on their educational and economic statuses, and were studied in terms of their choice of address terms. a discourse completion task was used as the data elicitation technique and chi-square was c...
conclusions this study showed that pcs and mcs score were slightly more than overall results while kdcs was slightly less than overall results. in addition, dialysis adequacy with kt/v between 1 and 1.2 is associated with lower rate of hospitalization. patients and methods a total of 6,930 chronic hemodialysis (hd) patients enrolled. kdcs-sf version 1.3 questionnaire was used to assess the heal...
Abnormal tau aggregates are presumed to be neurotoxic and are an important therapeutic target for multiple neurodegenerative disorders including Alzheimer's disease. Growing evidence has shown that tau intermolecular disulfide cross-linking is critical in generating tau oligomers that serve as a building block for higher-order aggregates. Here we report that a small molecule inhibitor prevents ...
conclusions in veterans' family, psychological health of the veterans and marital adjustment of the parents have a significant relationship with their children's quality of life and happiness. results global severity index (gsi) scores of veterans and veteran's age were inversely correlated with the scores of children's quality of life, while marital adjustment of parents and number of rooms in...
Background and Aim: The aggregation of misfolded proteins leads to various cellular malfunctions and disorders such as Alzheimer’s disease. The conventional treatments of such diseases often fail due to their inability to cross the blood-brain barrier. The ability of nanoparticles to influence protein folding and aggregation and, as a result, their potential therapeutic effect in diseases invol...
BACKGROUND/AIM Septic shock is an important health problem that vastly alters cardiovascular and hemodynamic status. Increased production of nitric oxide (NO) and endothelin is a counterpart of this endotoxemic state. This study was conducted to test the hypothesis that nonselective NO synthesis blocker (L-NAME), inducible NO synthesis blocker (L-canavanine), or endothelin receptor antagonist (...
Single-walled carbon nanotubes (SWCNTs) dispersed in aqueous media have many potential applications in chemistry, biology and medicine. To disperse SWCNTs into aqueous media, it is often necessary to modify the surface of SWCNTs by either covalent or noncovalent methods. As a result of this modification, the properties of SWCNTs may be profoundly influenced by the nature of the surface modifica...
Alzheimer’s disease (AD) is characterized by the abnormal aggregation of amyloid ß (Aß) peptide into insoluble fibrils called amyloid plaques. Preventing this process of fibrillization may offer effective therapy for treatment of AD. The aim of the present study is to investigate the effect of methanolic extracts of 13 plant species which are known to be brain boosters in Ayurvedic system of me...
Dominant mutations in Cu,Zn-superoxide dismutase (SOD1) cause a familial form of amyotrophic lateral sclerosis (fALS). Misfolding and aggregation of mutant SOD1 proteins are a pathological hallmark of SOD1-related fALS cases; however, the molecular mechanism of SOD1 aggregation remains controversial. Here, I have used E. coli as a model organism and shown multiple distinct pathways of SOD1 aggr...
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