INTRODUCTION Root canal disinfection is an important step in regenerative endodontic treatments. An ideal irrigating solution must have high antimicrobial activity and minimum cytotoxicity. This study sought to assess the effect of some irrigating solutions on stem cells from the human apical papilla (SCAP) after different periods of exposure. METHODS AND MATERIALS Stem cells were isolated fr...

During postembryonic development, all organs of a plant are ultimately derived from a few pluripotent stem cells found in specialized structures called apical meristems. Here we discuss our current knowledge about the regulation of plant stem cells and their environments with main emphasis on the shoot apical meristem of Arabidopsis thaliana. Recent studies suggest that stem cells are localized...

Alopecia is an exceedingly prevalent problem effecting men and women of all ages. The standard of care for alopecia involves either transplanting existing hair follicles to bald areas or attempting to stimulate existing follicles with topical and/or oral medication. Yet, these treatment options are fraught with problems of cost, side effects, and, most importantly, inadequate long-term hair cov...

A three-dimensional (3D) dentin/pulp tissue analogue, resembling the human natural has been engineered in an vitro setup, aiming to assess cytocompatibility of resin-based dental restorative cements. Stem Cells from Apical Papilla (SCAP) and Human Umbilical Vein Endothelial (HUVEC) were embedded Collagen-I/Fibrin hydrogels at 1:3 ratio within 24-well plates. Hanging culture inserts placed over ...

The avian basilar papilla is tonotopically organized such that hair cells along the sensory epithelium respond best to acoustic stimulation at differing frequencies. This specificity arises due to the mechanics of the cochlea itself and intrinsic electrical properties of the hair cells. Tall hair cells show membrane voltage oscillations in response to step current injection that may allow cells...