BACKGROUND AND PURPOSE Enrollment in the Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis (SAMMPRIS) trial was halted due to the high risk of stroke or death within 30 days of enrollment in the percutaneous transluminal angioplasty and stenting arm relative to the medical arm. This analysis focuses on the patient and procedural factors that may...

BACKGROUND Major side branch (SB) occlusion is one of the most serious complications during percutaneous coronary intervention (PCI) for bifurcation lesions. We aimed to characterize the incidence and predictors of major SB occlusion during coronary bifurcation intervention. METHODS We selected consecutive patients undergoing PCI (using one stent or provisional two stent strategy) for bifurca...

OBJECTIVES This study was conducted to determine whether direct stenting with TAXUS Liberté is noninferior to stenting after pre-dilation. BACKGROUND Direct stenting is performed in approximately 30% of patients, but data on clinical and angiographic outcomes with drug-eluting stents are limited. METHODS The TAXUS ATLAS DIRECT STENT is a single-arm, multicenter study that enrolled patients ...

OBJECTIVES This registry collected the 30-day and 9-month clinical outcomes of patients whose coronary stent implantation was suboptimal, and compared them with the cohort of patients with "optimal" stenting in the randomized portion of the STent Anti-thrombotic Regimen Study (STARS) trial. BACKGROUND Although "optimal" stenting combined with an aspirin and ticlopidine regimen carries a low (...

To date, only a few studies have compared the clinical efficacy of intracoronary ultrasound (IVUS)-guided to angiographically guided stenting. Furthermore, it is not yet known whether the lower restenosis rate shown with the former strategy would translate into a substantial clinical advantage. Therefore, the aim of the present investigation was to improve the level of evidence of these studies...

Cerebral hyperperfusion syndrome is a rare but serious complication of carotid revascularization, and characterized by ipsilateral headache, hypertension, seizures, focal neurological deficits. Therefore, treatment strategies are directed towards regulation blood pressure limitation rises in cerebral perfusion to prevent edema or hemorrhage, especially during several days after endarterctomy st...

Intravascular stents are tubular structures placed into stenotic artery to expand the inside passage and improve blood flow. The mechanical factors affect the restenosis after stenting and image-based simulation has become a popular tool for acquiring information. The aim of this study was to demonstrate quantitatively and qualitatively the hemodynamic changes in coronary artery after stent imp...

Along with the wide use of coronary stenting, adjunctive antiplatelet medications have been improved rapidly in the past decade. The role of ticlopidine plus aspirin in the prevention of subacute thrombosis after coronary stenting had been established. However, failure to prevent restenosis and high incidence of adverse effects remain the limitations of this regimen. Cilostazol, a newly develop...

Carotid artery stenting, compared with carotid endarterectomy, is emerging as an effective and less invasive method of revascularization for extracranial carotid artery stenosis. Carotid stenting is established as the treatment of choice for certain high-risk patient subsets, and ongoing clinical trials are evaluating this method across a broader clinical spectrum, including asymptomatic patien...

The present review assesses the data on long-term outcome after coronary stenting. Histological, angiographical and intravascular imaging data have shown that the insertion of stents constitutes only a transient stimulus to lumen renarrowing, that this process is almost complete at 6 months and that a certain degree of neointima regression is also possible after this time. Clinical data have co...