نتایج جستجو برای: steroid cell tumor
تعداد نتایج: 1950746 فیلتر نتایج به سال:
BACKGROUND/AIM Titanocene dichloride held great promise as a chemotherapeutic compound in pre-clinical studies. However, subsequent clinical trials revealed hepatoxicity and nephrotoxicity, which limited its use in clinical applications. Therefore, we used steroid pendant groups to improve the targeting of titanocene in MCF-7 breast cancer cells, and demonstrated a 10-fold lower effective dose ...
background and objective: p53 is a suppressive gene that plays a key role in dna repair and apoptosis. the purpose of this study was to investigate the effect of p53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (scc) response to neoadjuvant chemoradiotherapy. patients and methods: in this retrospective cohort study, 44 patients with loca...
introdouction: squamous cell carcinoma is the most common oral cancer and the prognosis because of a late diagnosis remains poor despite numerous treatments. therefore, we conducted a cross-sectional study to investigate the relationships between survival rate(sr) of oral squamous cell carcinoma (oscc) and clinical,demographic, pathological, and molecular factors in yazd city during 1998– 2008....
conclusions despite the fact that abnormalities in p53 and p27kip1 may be involved in the development of oscc, their clinical significance in the studied population seems limited. further investigation on the combined p53/p27kip1 expression may be helpful in predicting the biologic behavior of this tumor. results p53 and p27kip1 expression were found in 28.57% (8 positive versus 20 negative) an...
PURPOSE The interleukin 1 (IL-1) system plays an important role in human pathology and is involved in the local control of malignant disease. However, little is known about its expression in breast cancer and its correlation with prognostic parameters such as receptor status and grading. EXPERIMENTAL DESIGN The expression of IL-1alpha and other IL-1 family members was analyzed by reverse tran...
Sclerosing stromal tumor of the ovary is a rare, benign ovarian tumor, seen primarily in young women. We report a 3-year-old girl who presented with a palpable lower abdominal mass. Computed Tomography (CT) study revealed a huge pelvic mass with an enhancement pattern typical of ovarian sclerosing stromal tumor. The diagnosis was confirmed by pathology examination of the surgically resected tum...
Abstract Background Glioblastoma (GBM) is an aggressive brain tumor with a median survival of 14.6 months. We have no standard treatment for relapse and current options limited effect. Novel treatments are necessary to improve quality life. Material Methods present data from; phase II open label, two-armed clinical trial studying nivolumab bevacizumab in recurrent GBM, progression after Stupp’s...
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