How does a fertilized egg decode its own genome to eventually develop into a mature animal? Each developing cell must activate a battery of genes in a timely manner and according to the function it will ultimately perform, but how? During development of the notochord--a structure akin to the vertebrate spine--in a simple marine invertebrate, an essential protein called Brachyury binds to specif...

Organisms must adapt to seasonal changes in the environment and time their physiology accordingly. In vertebrates, the annual change in photoperiod is often critical for entraining the neuroendocrine pathways, which drive seasonal metabolic and reproductive cycles. These cycles depend on thyroid hormone (TH), reflecting its ancestral role in metabolic control. Recent studies reveal that--in mam...

Rural America has occupied an increasingly central role in the nation's consciousness since election of Donald Trump 2016 US presidential election. While highlighting a previously overlooked key constituency, this increased focus often had unfortunate effect further ostracizing and othering rural people places through gross characterizations stereotyping. News reports popular works fiction emph...

The article examines the zoomorphic code of a dog in culture Russian Ustians - descendants old-timers lower Indigirka. settlers, having adapted to harsh climate Arctic, created polar version culture, which dogs became an obligatory element. Their role commercial and economic activities is extremely great. Having become center everyday life, cultural sub-ethnic group. linguoculturological approa...

This paper presents an asynchronous implementation of a failure detector for unknown and mobile networks. Our approach does not rely on timers. Neither the composition nor the number of nodes in the system are known. Our algorithm can implement failure detectors of class ♦S when behavioral properties and connectivity conditions are satisfied by the underlying system.

There are quite a lot of formal models around, but they have very little use in real programming projects. Here high level Petri nets are put to the test in the building of an industrial analyzer for SDL, a programming language for distributed and concurrent processes with asynchronous communication. Problems with complex data types and the modeling of timers are discussed.

Abstract A study of 1,558 US households in June 2020 evaluated utilization online grocery shopping during the COVID-19 pandemic, influences on utilization, and plans for future shopping. Nearly 55 percent respondents shopped 2020; 20 were first-timers. Cragg model estimates showed likelihood frequency included demographics, employment, prior Illness concerns increased likelihood, while food sho...

Repeated chromatographic analyses of polyphenolic vine stalks extracts allowed us to note a huge adsorption difference on polyvinylidene fluoride (PVDF), between trans-resveratrol 1 and (+)-trans-ε-viniferin 2. We could optimize the conditions (solvent, saturation of the process), for this polymer to adsorb very selectively 2, with regard to the monomer 1 that remains in solution. Since membran...