We present a Data-Driven framework for multiscale mechanical analysis of materials. The proposed relies on the formulation in mechanics (Kirchdoerfer and Ortiz 2016), with material data being directly extracted from lower-scale computations. Particular emphasis is placed two key elements: parametrization history, optimal sampling state space. demonstrate an application prediction behavior sand,...

Abstract We describe a case of endogenous endophthalmitis caused by sequence type 66-K2 hypervirulent Klebsiella pneumoniae in diabetic patient with no travel history outside the United States. Genomic analysis showed pathogen has remained highly conserved, retaining >98% genetic similarity to original strain described Indonesia 1935.

1.1. Strategy and Techniques For a rock of given mineralogy and microstructure, the variables important in determining strength are pressure, temperature, strain, strain history, strain rate, pore fluid pressure, grain size, fugacities of water and other volatiles, and chemical activities of the mineral components. Although earth scientists may now duplicate pressures and temperatures appropria...

Muscle strain is a very common injury. Muscles that are frequently involved cross two joints, act mainly in an eccentric fashion, and contain a high percentage of fast-twitch fibers. Muscle strain usually causes acute pain and occurs during strenuous activity. In most cases, the diagnosis can be made on the basis of the history and physical examination. Magnetic resonance imaging is recommended...

A constitutive equation for nonlinear viscoelasticity is used to model the mechanical response of solid polymers such as polycarbonate. The nonlinearity arises from a reduced time which causes stress relaxation to accelerate with increasing strain. The constitutive equation can account for the occurrence of yield in a homogeneous uniaxial constant strain rate test. The constitutive equation is ...

The toughness of a polymer glass is determined by the interplay of yielding, strain softening, and strain hardening. Molecular-dynamics simulations of a typical polymer glass, atactic polystyrene, under the influence of active deformation have been carried out to enlighten these processes. It is observed that the dominant interaction for the yield peak is of interchain nature and for the strain...

The plastic deformation and ductile failure behaviors of anisotropic AISI 1018 low carbon steel C260 Cu-Zn brass under uniaxial tensile loading were investigated. full-filed surface U-notched sheet metal was measured by digital image correlation technique. Three-dimensional finite element modeling using the Hill model calibrated post-necking strain hardening curve performed to obtain force hist...

BACKGROUND Pulmonary exacerbations in cystic fibrosis (CF) remain poorly understood and treatment is usually targeted at Pseudomonas aeruginosa. Within Australia a predominant shared P. aeruginosa strain (AUST-02) is associated with greater treatment needs. This single centre study assessed temporal shared strain population dynamics during and after antibiotic treatment of exacerbations. METH...