To date, special attention should be paid to drugs that have antimicrobial, anti-inflammatory and wound-healing effects, one of which is sodium-containing drugs.
 The article presents the results experimental studies study acute toxicity drugs: glycetinate 2 %, its analogues – ovocid 3 potassium-sodium 1.5% (Na/K 1.5 %). was carried out by applying skin animals. experiment used white rats ...

background and objectives: salvia chloroleuca rech. f. & allen., is an endemic species growing wildly in north east and center parts of iran but there is no information about its safety. to provide information about the safety of the species, we evaluated its acute and sub chronic toxicity in rats. methods: in acute toxicity study, the aqueous methanol (80%) extract at a single dose of 2000...

Coriandrum sativum L. (CS) seeds are known to possess therapeutic potentials against a variety of physiological disorders. This study assesses acute and sub-chronic toxicity profile of hydro-methanolic extract of CS seeds using OECD guidelines. In acute toxicity study, mice were once orally administered 1000, 3000 and 5000 mg/kg body weight of CS extract. There were no any behavioral alteration...

Article history: Received on: 28/02/2014 Revised on: 02/04/2014 Accepted on: 22/04/2014 Available online: 28/04/2014 Acute and sub-chronic toxicity studies of the aqueous extract of the root bark of C. sieberiana (Caesalpiniaceae), a plant used locally in Ghana for the treatment of pain, was carried out in rodents. In the acute study, a single oral dose (5000 mg/kg) of the aqueous extract of C....

BACKGROUND Para-Dinitrobenzene (p-DNB) is one of the isomers of dinitrobenzene which have been detected as environmental toxicants. Skin irritation and organ toxicities are likely for industrial workers exposed to p-DNB. This study evaluated the effect of sub-chronic exposure of rats to p-DNB on cellular redox balance, hepatic and renal integrity. METHODS Forty eight male Wistar rats weighing...

BACKGROUND Previously, we have reported that most, if not all, of the Scyphozoan jellyfish venoms contain multiple components of metalloproteinases, which apparently linked to the venom toxicity. Further, it is also well known that there is a positive correlation between the inflammatory reaction of dermal tissues and their tissue metalloproteinase activity. Based on these, the use of metallopr...