In this paper, we propose a case-based approach for characterizing and analyzing subgroup patterns: We present techniques for retrieving characteristic factors and cases, and merge these into prototypical cases for presentation to the user. In general, cases capture knowledge and concrete experiences of specific situations. By exploiting case-based knowledge for characterizing a subgroup patter...

Department of Physiology, University of Sydney, Sydney, NSW. David I Cook, MD, FRACP, Professor of Cellular Physiology. NHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW. Val J Gebski, BA, MStat, Associate Professor and Principal Research Fellow; Anthony C Keech, MScEpid, FRACP, Deputy Director. Reprints will not be available from the authors. Correspondence: Professor David I...

We introduce a Bayesian method, LASSOplus, that unifies recent contributions in the sparse modeling literatures, while substantially extending pre-existing estimators in terms of both performance and flexibility. Unlike existing Bayesian variable selection methods, LASSOplus both selects and estimates effects while returning estimated confidence intervals among discovered effects. Furthermore, ...

Background and Objective: Leishmaniasis is among the seven more significant tropical diseases, and it is a major global health issue with a wide range of clinical symptoms and potentially lethal consequences. Resveratrol and its derivatives have been shown to have anti-Leishmanial properties. This study aimed to use a meta-analysis of relevant papers to determine the leishmanicidal impact of re...

Abstract_ Introduction: Viola plant has been used traditionally for the treatment of neurological disorders. We aimed at determining whether pretreatment with Viola spathulata extract can alleviate the severity of ischemic-reperfusion damages and it can exert its protective effects through the regulation of a sodium/calcium exchanger (NCX3) gene expression in a rat brain. Methods: Male Wistar r...

introduction: ultrasonography is currently being used as one of the diagnostic modalities in various medical emergencies for screening of trauma patients. the diagnostic value of this modality in detection of traumatic chest injuries has been evaluated by several studies but its diagnostic accuracy in diagnosis of pulmonary contusion is a matter of discussion. therefore, the present study aimed...

 Objective: To evaluate the association of base deficit (BD) with mortality in traumatized children, and to assess this association in a subgroup of patients with traumatic brain injury (TBI).   Methods: In this cross-sectional study performed prospectively on a convenience sample of patients under 16 years of age with trauma presenting to an academic lev...

As many scientific applications require large data processing, the importance of parallel I/O has been increasingly recognized. Collective I/O is one of the considerable features of parallel I/O and enables application programmers to easily handle their large data volume. In this paper we measured and analyzed the performance of original collective I/O and the subgroup method, the way of using ...

Several authors have suggested that burned out patients do not form a homogeneous group and that subgroups should be considered. The identification of these subgroups may contribute to a better understanding of the burnout construct and lead to more specific therapeutic interventions. Subgroup analysis may also help clarify whether burnout is a distinct entity and whether subgroups of burnout o...