Background and objective: Analgesia is of the main goals of anesthesiology. For this purpose, various medications and methods are used. One of these drugs is bupivacaine. Opioids such as sufentanil are used in spinal anesthesia in order to increase the duration of analgesia, reduce the complications, and improve the quality of anesthesia. The present study aimed to compare analgesia with or wit...

conclusions the length of sensory and motor blockade is shorter in chronic opioid abusers. adding 10 µg sufentanil to hyperbaric bupivacaine in opium abusers lengthened the sensory and motor block duration. results the duration of sensory and motor block were significantly less in group c (537.0 ± 40.1 minutes, 479.0 ± 34.8 minutes) and the longest duration of sensory and motor block was observ...

BACKGROUND The intraoperative wake-up test is a standard procedure for early recognition of neurologic complications after posterior correction of idiopathic scoliosis. In this prospective, single-blinded cohort study, the impact of the wake-up test and the opioid used for anesthesia on the quality of the patients' sleep after scoliosis surgery was investigated up to 12 months postoperatively. ...

Repeated boluses of i.v. morphine are often used for analgesia after cardiac surgery, but this procedure frequently provides inadequate pain relief. Target controlled infusion (TCI) of opioid drugs has been proposed as an alternative. The objective of this study was to evaluate the effects of prolonged sufentanil TCI adjusted to an effort pain score on the postoperative course after cardiac sur...

BACKGROUND The relative potencies of alfentanil, fentanyl, and sufentanil as a risk factor for postoperative nausea and vomiting have not been determined. They were compared in a randomized study designed to obtain equipotent plasma concentrations of these three opioids at the beginning of the recovery period. METHODS The study included 274 patients treated on an outpatient basis. The steady ...

To the Editor: We concur with the promising experience reported by Dr. Gardner-Nix 1 in using transmucosal (sublingual) sufentanil for incident pain. We wish to report preliminary data from a pilot study of nasal transmucosal administration of this drug for breakthrough pain in an acute hospital-based palliative care unit. Up to 60% of patients with cancer-associated pain suffer from episodes o...

BACKGROUND Anaesthesia in rabbits is associated with a high mortality rate, compared to that in cats and dogs. Total intravenous anaesthesia (TIVA) with drugs that provide cardiovascular stability and are rapidly metabolised could be of benefit for use in rabbits. The aim was to evaluate cardiorespiratory effects of TIVA with sufentanil-midazolam in eight New Zealand White rabbits. Subcutaneous...

Inhalational anesthetics have demonstrated cardioprotective effects against myocardial ischemia-reperfusion injury. Clinical studies in cardiac surgery have supported these findings, although not with the consistency demonstrated in experimental studies. Recent investigations have questioned the advantages of inhalational over intravenous anesthetics with respect to cardiac protection. Ketamine...

BACKGROUND Intrathecal administration of opioids may cause lower urinary tract dysfunction. In this study, the authors compared the effects of morphine and sufentanil administered intrathecally in a randomized double-blind fashion (two doses each) on lower urinary tract function in healthy male volunteers. METHODS Urodynamic evaluation was performed before and every hour after drug administra...

BACKGROUND Relative effects of dosage, volume and concentration of local anaesthetics used for postoperative thoracic epidural analgesia are still under debate. In this randomized, prospective, double-blinded study, we evaluated the incidence of side-effects such as changes in arterial pressure, postoperative nausea, vomiting, and pruritus in patients admitted for thoracic surgery during contin...