Methods: The antioxidant potential of pyrrolo [1, 2-A] pyrazine-1, 4-dione, hexahydro-3-(2-methylpropyl) (diketopiperazine) extracted from Streptomyces sp. VITMK1 was studied using reducing power assay. The scavenging of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical and nitric oxide (NO) radical by the compound was also studied. The cytotoxic activity of the compound on RAW 264.7 macrophage cel...

We study the allylic oxidation of cyclohexene with O2 under mild conditions in the presence of transition-metal catalysts. The catalysts comprise nanometric metal oxide particles supported on porous N-doped carbons (M/N:C, M=V, Cr, Fe, Co, Ni, Cu, Nb, Mo, W). Most of these metal oxides give only moderate conversions, and the majority of the products are over-oxidation products. Co/N:C and Cu/N:...

Costus speciosus (Koen) J.E. Sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. In the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by DPPH radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...

The water and MeOH extracts of the stems of Quercus coccifera L. are screened for their radical scavenging activity against 2,2-diphenyl-1-picryl hydrazyl (DPPH), superoxide (SO) and nitric oxide (NO) radicals spectroscopically. Dose dependent radical scavenging activity was observed and the results were found to be comparable to that of known antioxidant compounds BHA (3-t-butyl-4-hydroxyaniso...

The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark, leaves and fruits were performed. Leaves and bark extracts exhibits highest f...

New benzodiazaphosphorin-2-oxide derivatives 3 were synthesized with the aim of evaluating in vitro their antioxidant properties related to DPPH radical scavenging, ferric reducing power (FRP), hydroxyl radical scavenging and ferrous ion chelating activity (FIC). The structures of the new compounds were confirmed and characterized on the basis of their infrared and nuclear magnetic resonance sp...

The oxidation of L-cysteine by horseradish peroxidase in the presence of oxygen forms a thiyl free radical as demonstrated with the spin-trapping ESR technique. Reactions of this thiyl free radical result in oxygen consumption, which is inhibited by the spin trap 5,5'-dimethyl-1-pyrroline-N-oxide. Cysteine sulfinic acid, a cysteine metabolite, is a poorer substrate for horseradish peroxidase th...

In the present study, coarse powder of Scindapsus officinalis (Roxb.) Schott. fruit was extracted successively using hexane, chloroform, ethyl acetate and 50% ethanol. The ethyl acetate and 50% ethanolic extracts were investigated for its antioxidant activity by using nitric oxide and DPPH radical scavenging methods. The IC value was also calculated. Ascorbic acid was used as standard. Both the...

The objective of the study was to investigate the anti-oxidant and anti-inflammatory effect of aqueous extract of Ocimum sanctum leaf. The antioxidant and anti-inflammatory activities were evaluated using in vitro Ferric reducing power, Free radical scavenging activity by DPPH method, hydroxyl radical scavenging activity, Nitric oxide radical scavenging activity, Hyaluronidase inhibition assay....

Both singlet oxygen and the hydroxyl radical are generated in mammalian ccHs by UVA (~3Z0---~3{50 rim) and possibly near-visible (~{50--420 nm) radiation. We have modulated the cellular levels of these two reactive oxygen species in order to compare their involvement in the induction of the human heme 0xygenase (I40) gene by broad spectrum UVA/nearvisible light 0LIVA/NVL). Irradiation in deuter...