We report on a patient in whom intractable infectious keratitis and subsequent lamellar flap necrosis necessitating flap amputation after laser in situ keratomileusis (LASIK). A 34-year-old woman undergoing LASIK complained of blurred vision and pain in the left eye. The best spectacle-corrected visual acuity was 0.01, and slit-lamp examination showed a marked presence of stromal infiltrates in...

INTRODUCTION Surgical organ preservation approaches constitute important treatment options for laryngeal cancer. Supracricoid partial laryngectomies (SCPLs) are open surgical techniques designed to resect selected advanced endolaryngeal tumors without major invasion of the infraglottis, involvement of the posterior commissure, or fixation of the cricoarytenoid (CA) joint. One of the key oncolog...

Effective obliteration of dead space after reconstructive surgery facilitates a good cosmetic outcome and prevention of delayed wound healing and recurrent infection.We evaluated the efficacy of a keystone-designed buried de-epithelialized (KBD) flap for the obliteration of small to moderately sized surgical dead spaces.We reviewed the medical records of patients who received a KBD flap followi...

AIM The aim of this study was to evaluate almost 20 years of using the pectoralis major flap in head and neck reconstruction at the Department of Maxillofacial Surgery, Zagreb. PATIENTS In the period from 1981 to 1999, a total of 506 pectoralis major flaps were used for head and neck reconstruction in 500 patients. In all cases the flap was used after surgical resection of an advanced maligna...

The pedicled anterolateral thigh (ALT) flap based on septocutanous or musculocutanous perforators of the lateral circumflex femoral system is a reliable flap. The use of ALT flap as a pedicled flap is relatively unpopular if compared with its use as a free flap. The flap can be raised as a fasciocutaneous or muscle flap or myocutaneous flap. The pedicled flap has got a lengthy pedicle with a li...

Canine amniotic membrane (AM) transplantation in conjunction with a third eyelid flap was used to promote healing of created deep corneal ulcers in 6 normal mongrel dogs. The healing was compared with the healing of created ulcers in the other eye of the same dog that were treated only with the third eyelid flap. A minimum of 60 days interval was allowed between the two treatment procedures in ...

Local administration of calcitonin gene-related peptide (CGRP) has been shown to improve tissue survival in surgical skin flaps. Moreover, topical CGRP has been demonstrated to exert anti-inflammatory effects in different animal models of skin inflammation. The aim of the present study was to establish whether systemic treatment with low doses of CGRP may improve survival and reduce neutrophil ...

BACKGROUND As the indications for expanded endonasal approaches continue to evolve, alternative reconstructive techniques are needed to address increasingly complex surgical skull base defects. In the absence of the nasoseptal flap, we describe our experience with the posterior pedicle inferior turbinate flap (PPITF) in skull base reconstruction. DESIGN Case series. SETTING Academic tertiar...

background one of the main challenges in skin flap surgery is tissue ischemia and following necrosis. the present study compares the effects of fibroblast growth factors 1 and 2 on increasing cutaneous vasculature, improving ischemia, and preventing distal necrosis in ischemic skin flaps in rat model. methods thirty rats were allocated into 3 groups (n=10) and 2×8 cm dorsal random-pattern skin ...

BACKGROUND surgical excision remains the best tool for management of skin tumors affecting nasal skin, however many surgical techniques have been used for reconstruction of the nasal defects caused by excisional surgery. The aim of this work is the evaluation of the feasibility and outcome of levator anguli oris muscle based flaps. METHODS Ninety patients of malignant nasal skin tumours were ...