The indolizidine alkaloid swainsonine (SW) is an inhibitor of lysosomal alpha-mannosidase reported to have antimetastatic activity in animal models. The cells grown in its presence develop truncated (hybrid) surface oligosaccharides that may alter their functional properties dependent on interactions of various ligands with membrane receptors. In the present study we observe that SW enhances st...

SW-163C and E are novel antitumor antibiotics, which belong to quinomycin family, isolated from the culture broth of Streptomyces sp. SNA15896. These compounds were determined to be cyclic depsipeptides having 3-hydroxyquinaldic acid as a chromophore and a sulfur-containing intramolecular cross linkage through various spectroscopic analyses.

The main argument of this paper is that Natural Language Processing (NLP) does, and will continue to, underlie the Semantic Web (SW), including its initial construction from unstructured sources like the World Wide Web (WWW), whether its advocates realise this or not. Chiefly, we argue, such NLP activity is the only way up to a defensible notion of meaning at conceptual levels (in the original ...

Increasingly, software (SW) in embedded systems can be updated due to the rising share of flashable electronic control units (ECUs). However, current SW installation procedures are insecure: An adversary can install SW in a given ECU without any sender authentication or compatibility assessment. In addition, SW is installed on an all-or-nothing basis: With the installation, the user acquires fu...

The aim is to explain the current issues of HW/SW cosimulation and to introduce a new challenge of HW/SW cosimulation for multiprocessor SoC (MPSoC). Most of the current issues are related to raising abstraction levels of HW/SW cosimulation. Mixed-level cosimulation is explained in a unified manner using a concept of ‘HW/SW interface’. First, abstraction levels in HW/SW cosimulation are explain...

We investigated the effects of applying an external electric field on electronic properties Stone-Wales (SW) defective carbon-boron-nitride nanotubes (CBN) using first principles calculations. The CBN were modeled by introducing Stone–Wales defects in boron-nitride segment (BN-SW), carbon (C-SW), and interface (CBN-SW). Initially, we studied formation energies structural stability for all model...

This paper introduces the concept of a dynamic key infrastructure for Grid. It utilises the properties of Identity-based Cryptography (IBC) to simplify key management techniques used in current Public Key Infrastructure (PKI) settings for Grid. This approach can offer greater simplicity, flexibility, and enhanced computation trade-offs.

Tectonic stresses governed by the Arabia – Central Iran collision are transferred throughout Iranian Plateau. The orientation of maximum horizontal stress (σ 1 ) significantly changes (~90°) in Persian block NW Iran. However, exact spatial extent and boundary conditions for these poorly defined. This study investigates late Cenozoic regime a key region including Mahneshan Mianeh Basin (MMCB), G...