Increased energy consumption, especially increased consumption of sweet energy-dense food, is thought to be one of the main contributors to the escalating rates in overweight individuals and obesity globally. The individual's ability to detect or sense sweetness in the oral cavity is thought to be one of many factors influencing food acceptance, and therefore, taste may play an essential role i...

Hypertensive (SHR) and nonhypertensive [Wistar-Kyoto (WKY); Sprague-Dawley (SD)] strains of rats received the dipeptide sweetener aspartame (200 mg/kg) or, as a positive control, tyrosine (200 mg/kg) by gavage or parenterally, after a brief (2-h) fast. Two hours later, compared with those of saline controls brain levels of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylethylethyleneglyc...

In September of 2000, McNeil Nutritionals began marketing Splenda, its new no-calorie sweetener, using the tagline “made from sugar so it tastes like sugar.”1 The company spent approximately $235 million in advertising and promotional materials to establish its unique brand identity that capitalizes on Splenda’s sugar origin and sugar-like taste.2 The campaign was effective—in 2007, Splenda was...

BACKGROUND Dietary sweeteners may contribute to metabolic dysregulation and cardiovascular disease (CVD), but this has not been assessed in human immunodeficiency virus (HIV). METHODS One hundred twenty-four HIV-infected and 56 non-HIV-infected participants, without history of known coronary artery disease were included. Dietary intake was assessed using a 4-day food record. Coronary plaque w...

OBJECTIVE To analyze the consumption of sweeteners and dietetic foods by individuals with type 2 diabetes, assisted by the Brazilian National Health System, in the city of Ribeirão Preto, SP. SUBJECTS AND METHODS Through a questionnaire were interviewed 120 patients were interviewed, stratified by sex, age and level of health care. RESULTS The use of sweeteners is very frequent by the popul...