نتایج جستجو برای: synapsis

تعداد نتایج: 898  

Journal: :Cell 2004
Douglas K Bishop Denise Zickler

During meiosis, DNA double-strand breaks ultimately yield two types of recombinants: crossovers (CO) and noncrossovers (NCO). Recent studies in budding yeast show the CO/NCO designation occurs before stable strand exchange and thus well before Holliday junction resolution. Chromosome synapsis occurs after CO/NCO designation and is not required for the regulated distribution of COs along chromos...

Journal: :Genetics 2005
John Locke Heather E McDermid

Although mitosis and meiosis are fundamental to understanding genetics, students often find them difficult to learn. We suggest using common "pool noodles" as teaching aids to represent chromatids in classroom demonstrations. Students use these noodles to demonstrate the processes of synapsis, segregation, and recombination. Student feedback has been overwhelmingly positive.

Journal: :PloS one 2016
Nicolas Mary Harmonie Barasc Stéphane Ferchaud Aurélia Priet Anne Calgaro Anne-Marie Loustau-Dudez Nathalie Bonnet Martine Yerle Alain Ducos Alain Pinton

Correct pairing, synapsis and recombination between homologous chromosomes are essential for normal meiosis. All these events are strongly regulated, and our knowledge of the mechanisms involved in this regulation is increasing rapidly. Chromosomal rearrangements are known to disturb these processes. In the present paper, synapsis and recombination (number and distribution of MLH1 foci) were st...

2009
Marcia Manterola Jesús Page Chiara Vasco Soledad Berríos María Teresa Parra Alberto Viera Julio S. Rufas Maurizio Zuccotti Silvia Garagna Raúl Fernández-Donoso

Meiosis is a complex type of cell division that involves homologous chromosome pairing, synapsis, recombination, and segregation. When any of these processes is altered, cellular checkpoints arrest meiosis progression and induce cell elimination. Meiotic impairment is particularly frequent in organisms bearing chromosomal translocations. When chromosomal translocations appear in heterozygosis, ...

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