32 A toxicovenomic study was performed on the venom of the green mamba, 33 Dendroaspis angusticeps. Forty-two different proteins were identified in the venom of 34 D. angusticeps, in addition to the nucleoside adenosine. The most abundant proteins 35 belong to the three-finger toxin (3FTx) (69.2%) and the Kunitz-type proteinase inhibitor 36 (16.3%) families. Several sub-subfamilies of the 3FTxs...

Dynamic gas–liquid mass-transfer processes are extensively encountered in mixture transport systems, where mechanical pumps pressurize the and accompanied by flow instabilities. Herein, our proposed gaseous cavitation model was innovatively developed to revolutionize independent unidirectional absorbed or evolved mass transfers. Complex behaviors under synergetic effects of vapor cavitations we...

Ischemic stroke is a common cerebrovascular disease with substantial morbidity and mortality worldwide. However, therapeutic options to minimize the cerebral ischemia-reperfusion (I/R) injury are limited. In China, combination of herb Danshen (Salvia miltiorrhiza Bge) and Honghua (Carthamus tinctorius L.) is effective for stroke treatment in patients but its underlying mechanism requires furthe...

In many cells systems, the cellular interaction between two or more humoral factors leads to a synergistic response in terms of cellular growth and function. In particular, the growth and differentiation of hematopoietic progenitor cells involves numerous synergistic interactions between colony-stimulating factors (CSFs) that individually stimulate hematopoiesis (granulocyte-CSF, granulocyte-ma...

In this study, the synergistic effects of abrasion and corrosion on UNS S30403, S31603 and S32760 stainless steels have been investigated using micro-abrasion test rig. The stainless steel samples have been studied under both pure abrasion (PA) and abrasion–corrosion (AC) conditions imulated by using silicon carbide based slurries in either distilled water or 3.5% sodium chloride solutions. Tes...

Nitric oxide (NO) derived from inducible NO synthase (iNOS) at sites of inflammation is closely related to host defense against infection and airway inflammation. Cytokines are known to stimulate NO production in human alveolar epithelial cells in a synergistic (nonlinear or nonadditive) manner. The mechanism of this synergy is not known. We measured the activation of the transcription factor N...

Inactivation of the Rb tumor suppressor can lead to increased cell proliferation or cell death depending on specific cellular context. Therefore, identification of the interacting pathways that modulate the effect of Rb loss will provide novel insights into the roles of Rb in cancer development and promote new therapeutic strategies. Here, we identify a novel synthetic lethal interaction betwee...

A synergistic effect between anatase and rutile TiO2 is known, in which the addition of rutile can remarkably enhance the photocatalytic activity of anatase in the degradation of organic contaminants. In this study, mixed-phase TiO2 nanocomposites consisting of anatase and rutile nanoparticles (NPs) were prepared for use as photoanodes in dye-sensitized solar cells (DSSCs) and were characterize...