A few months before the COVID-19 pandemic, Pierre Vogel and Kendall N. Houk published with a new textbook Wiley-VCH, “Organic Chemistry: Theory, Reactivity, Mechanisms in Modern Synthesis”, foreword from late Roberts H. Grubbs. The book demonstrates how catalytic processes dominate all fields of modern organic chemistry synthesis, invention combines thermodynamics, kinetics, spectroscopy, quant...

facile and versatile procedures have been explored for the synthesis of tetrahydropyridines and 2,3-dihydroquinazolin-4(1h)-ones. these protocols employ the one-pot multi-component condensation of arylaldehydes and aromatic amines with β-keto esters and isatoic anhydride in chloroacetic acid, respectively. the reactions proceeded smoothly to generate the corresponding products in high yield. we...

2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide ri...

In this paper we will present a formal framework, based on the notion of extraction calculus, which has been successfully applied to define procedures for extracting information from constructive proofs. Here we will apply such a mechanism to give a proof-theoretic account of SLD-derivations. We show how proofs of suitable constructive systems can be used in the context of deductive synthesis o...

Skin synthesis is important for the actual appearance of digital human models. However, it is difficult to design a general algorithm to efficiently produce high quality results. This paper proposes a parallel texture synthesis method for large scale skin of digital human models. Two major procedures are included in this method, a parallel matching procedure and a multi-pass optimizing procedur...

Optimization algorithms used in binary multi-level logic synthesis, such as network simplification, logic extraction, and resubstitution, have been treated independently and did not share computational procedures. Using multi-valued logic synthesis, some common conceptual and computational cores underlying these algorithms can be identified. We present an overview of a Boolean paradigm in multi...

PURPOSE To assess the activities of the two enzymes required for glutathione synthesis, gamma-glutamylcysteine synthetase and glutathione synthetase, in various forms of human cataracts. METHODS The Cooperative Cataract Research Group cataract classification method and standard enzyme assay procedures were used. RESULTS An inverse relationship was shown between residual activity of each of ...

The design principles and collection procedures behind a speech synthesis corpus directly impact the performance of the resulting text-to-speech system. This paper describes the design and collection of the Victoria corpus, created to support speech synthesis research and development at Apple Computer. This corpus is composed of ve constituent parts, each designed to cover a speci c aspect of s...