Systemic lupus erythematosus (SLE) is an autoimmune disease and a chronic systematic disease with unknown etiology influential more than one million individuals each year. The aim of this study is to substantiation the impact of IL4, C3 and C4 in patients with Systemic Lupus Erythematosus. During the period 2/January/2013 to 1/October/2013, fifty patients with Systemic Lupus Erythematosus that ...

Background: Interleukin (IL)1a and IL1b, and their endogenous receptor antagonist (IL1Ra), have been related to the pathology of systemic lupus erythematosus (SLE), but the role of IL1 polymorphisms in the aetiology of SLE is unknown. Objective: To examine polymorphisms at IL1a 2889(CRT), IL1a +4845(CRT), IL1b 2511(CRT), IL1b +3953(GRT), and IL1Ra (86 bp VNTR) in a population based study of SLE...

Systemic lupus erythematosus (SLE) is a heterogeneous multisystemic autoimmune disease of unknown etiology of variable course and outcome. It affects predominantlywomen (9:1) on their reproductive age years but can occur at the extremes of life (from infants to nonagenarians). In older adults the disease is not very severe, yet because it occurs in persons who may already have other comorbiditi...

Background. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a common finding of renal involvement which is related to high incidence of mortality and morbidity. IL-6 is produced by leukocytes and intrinsic kidney cells that affects inflammation, increases mesangial cell proliferation, and also contributes to autoimmunity. Objective. To detect the serum level as well as ...

Background: We have been determined that for patients with systemic lupus erythematosus (SLE), after becoming infected with tuberculosis, the damages in their hematologic and complement systems were alleviated to a certain extent, this was an interesting phenomenon. So we hypothesized that tuberculosis infection could be useful for treating the SLE activity. Methods: In order to verify the abov...

2014 Aim: The aim of this study was to determine the relationship between thyroid disorders and prolactin in patients with and without lupus activity. Patients & methods: Women with systemic lupus erythematosus (SLE) were evaluated for lupus activity. Serum tri-iodothyronine (T3), serum thyroxine (T4) and thyroid-stimulating hormone (TSH), anti-thyroid peroxidase (anti-TPO) anti-thyroglobulin (...

We argue that the possibility to observe a stable biaxial nematic phase in a binary mixture of prolate and oblate hard particles is seriously limited by the existence of entropydriven demixing. This result follows from a simple Onsager-type density functional theory. An important feature15 the coupling of the demixing mechanism to the orientational order of the system. The strength of this coup...