نتایج جستجو برای: systemic mastocytosis
تعداد نتایج: 175955 فیلتر نتایج به سال:
BackgroundIndolent systemic mastocytosis (ISM) is a clonal mast-cell disease driven by the KIT D816V mutation. We assessed efficacy and safety of avapritinib versus placebo, both with best supportive care, in patients ISM.MethodsWe randomized moderate to severe ISM (total symptom score [TSS] ≥28; scores range from 0 110, higher numbers indicating more symptoms) two one 25 mg once daily (n=141) ...
Mastocytosis can be associated with other clonal or non-clonal hematologic diseases as well as a variety of non-hematologic malignancies. A 75-year-old Caucasian male patient was referred to us with a 5-month history of neutrophilic leukocytosis and mild splenomegaly. He had developed a cutaneous melanoma sixteen years ago. According to the clinical and pathological features, a final diagnosis ...
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