BACKGROUND Strawberry (Fragaria x ananassa) is an economically important soft fruit crop with polyploid genome which complicates the breeding of new cultivars. For certain traits, genetic engineering offers a potential alternative to traditional breeding. However, many strawberry varieties are quite recalcitrant for Agrobacterium-mediated transformation, and a method allowing easy handling of l...

The time of onset and magnitude of cold-induced vasodilatation (CIVD) in six older men (62-70 years) were compared with those of seven younger men (20-29 years) by using a modified local cold tolerance test. This test consisted of a 10-min immersion of the left middle finger in cold water at 10 degrees C, and was substituted for a conventional test (30-min immersion in ice water at 0 degrees C)...

UNLABELLED Adenosine and adenosine analogs induce analgesia in humans and presumed antinociception in animal models when administered both systemically and intrathecally. In the present investigation in rats, we studied the effects of intrathecally administered adenosine analogs, with or without systemic coadministration of an adenosine antagonist (theophylline), on substance P (SP) and calcito...

The purpose of this study was to examine the influence of waterproof covering on finger skin temperature (FST) and hand pain during immersion test for diagnosing hand-arm vibration syndrome complying with the proposal of the International Organization for Standardization (ISO/ CD14835-1, 2001) for measurement procedure. Six healthy male subjects took part in the immersion tests and immersed the...

Since it is known that alloxan will react with many substances, and because preliminary unpublished work in this laboratory suggested that ascorbic acid potentiated the action of alloxan, the effect of ascorbic acid on the diabetogenic action of alloxan was investigated. Experimental. Hooded rats weighing approximately 250 g were used in this study. These animals were fed Purina Dog Chow during...

Rhodiola rosea L. (Crassulaceae) have been used as traditional medicines that can increase someone’s physical strength, work productivity, longevity and resistance to high altitude sickness, fatigue, depression, anaemia, gastrointestinal ailments, infections, and nervous system disorders. The objective of this study was to evaluate the anti-inflammatory and analgesic activities from the methano...

In continuing the search for new analgesics among derivatives of 2,1-benzothiazines, a series of corresponding toluidides and xylidides of 4-hydroxy-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylic acid has been synthesized by the reaction of ethyl 4-hydroxy-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylate with equimolar amounts of mono- and dimethyl-substituted anilides in boiling dry xylene. Their...

In the present study, we evaluate the analgesic activity of methanolic extract obtained from Jatropha unicostata balf leaves, using chemical and thermal models which will induce acute pain in mice and rats. This study was carried out by using sex Swiss mice (20-30gm) and wistar male rats (200-250gm).The methanolic extract was prepared by using maceration at room temperature (25°) over the perio...