نتایج جستجو برای: tandem repeats

تعداد نتایج: 74509  

Journal: :GEN biotechnology 2022

Huntington disease (HD) is one of a growing number rare genetic diseases characterized by the inheritance an increased short tandem repeats within affected gene. Many these repeat expansion disorders (REDs) affect brain. Although mutant allele necessary first step for manifestation, second further inherited expanded repeats, particularly in neurons brain, also appears to play critical role towa...

Journal: :Biotechnology in Animal Husbandry 2018

2006
Mohamed Y. Eltabakh Walid G. Aref Mourad Ouzzani Mohamed H. Ali

Consensus patterns, like motifs and tandem repeats, are highly conserved patterns with very few substitutions where no gaps are allowed. In this paper, we present a progressive hierarchical clustering technique for discovering consensus patterns in biological databases over a certain length range. This technique can discover consensus patterns with various requirements by applying a post-proces...

Journal: :Cancer research 1993
J D Fontenot N Tjandra D Bu C Ho R C Montelaro O J Finn

Until recently mucin tandem repeat protein cores were believed to exist in random-coil conformations and to attain structure solely by the addition of carbohydrates to serine and threonine residues. Matsushima et al. (Proteins Struct. Funct. Genet., 7: 125-155, 1990) recently proposed a model of the secondary structure of proline rich tandem repeat proteins that has challenged this idea, especi...

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