Likelihood approaches for large irregularly spaced spatial datasets are often very difficult, if not infeasible, to use due to computational limitations. Even when we can assume normality, exact calculations of the likelihood for a Gaussian spatial process observed at n locations requires O(n) operations. We present a version of Whittle’s approximation to the Gaussian log likelihood for spatial...

A test based on tapering is proposed for use in testing a global linear hypothesis under a functional linear model. The test statistic is constructed as a weighted sum of squared linear combinations of Fourier coefficients, a tapered quadratic form, in which higher Fourier frequencies are down-weighted so as to emphasize the smooth attributes of the model. A formula is QOPT n = n ∑pn j=1 j−1/2‖...

*Recent research suggests that increasing conduit tapering progressively reduces hydraulic constraints caused by tree height. Here, we tested this hypothesis using the tallest hardwood species, Eucalyptus regnans. *Vertical profiles of conduit dimensions and vessel density were measured for three mature trees of height 47, 51 and 63 m. *Mean hydraulic diameter (Dh) increased rapidly from the tr...

The rate of recurrence of subacute thyroiditis (SAT) during prednisolone (PSL) therapy is approximately 10 to 20%. However, there is little or no information on the time period to relapse following administration of a tapered dose of PSL and the factors associated with such relapse. The aim of this study was to determine the correlation between SAT recurrence and PSL tapering regimen used in th...

The Matérn covariance function is a popular choice for modeling dependence in spatial environmental data. Standard Matérn covariance models are, however, often computationally infeasible for large data sets. In this work, explicit computationally efficient wavelet Markov approximations of Gaussian Matérn fields are derived using Hilbert space approximations. Using a simulation-based study, the ...

Baillargeon L, Landreville P, Verreault R, et al. Discontinuation of benzodiazepines among older insomniac adults treated with cognitive-behavioural therapy combined with gradual tapering: a randomized trial. CMAJ 2003;169:1015–20. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

We report the clinical features of six patients with the Cohen syndrome. The characteristic features include mental retardation, truncal obesity, prominent incisors, and tapering digits. Pelviureteric obstruction and epilepsy are reported as possible new features of this syndrome.

We propose a simple graphical approach to steady state solutions of the cable equation for a general model of dendritic tree with tapering. A simple case of transient solutions is also briefly discussed.

Background • This case illustrates the relationship between gut, hormonal, and brain function in that dietary change, mindfulness interventions, and detoxification led to resolution of disabling luteally exacerbated psychiatric symptoms. Summary • A 45-y-old, married, Caucasian female with a history of diagnosed bipolar disorder with psychotic features, premenstrual dysphoric disorder, panic di...

Second-order intensity interferometry was employed to study the spatial and temporal properties of European X-ray Free-Electron Laser (EuXFEL). Measurements were performed at soft x-ray Self-Amplified Spontaneous Emission (SASE3) undulator beamline a photon energy 1.2 keV in (SASE) mode. Two high-power regimes SASE3 settings, i.e., linear quadratic tapering saturation, studied detail compared w...