نتایج جستجو برای: targeted radiation therapy microdosimetry

تعداد نتایج: 973977  

2016
Hem D Shukla

Radiation therapy (RT) is one of the highly effective treatments option for clinically advanced tumor, and plays a prominent role in cancer therapy and prognosis. It is estimated that 62% of newly diagnosed cancer patients are treated with radiation therapy [1]. The efficacious radiation therapy depends upon the homogenous delivery of total dose which could eliminate tumor cells while protectin...

Journal: :The Journal of urology 2007
J Trachtenberg A Bogaards R A Weersink M A Haider A Evans S A McCluskey A Scherz M R Gertner C Yue S Appu A Aprikian J Savard B C Wilson M Elhilali

PURPOSE Tookad is a novel intravascular photosensitizer. When activated by 763 nm light, it destroys tumors by damaging their blood supply. It then clears rapidly from the circulatory system. To our knowledge we report the first application of Tookad vascular targeted photodynamic therapy in humans. We assessed the safety, pharmacokinetics and preliminary treatment response as a salvage procedu...

2016
Jalal Arabloo Pejman Hamouzadeh Seyedeh Maryam Mousavinezhad Mohammadreza Mobinizadeh Alireza Olyaeemanesh Morvarid Pooyandjoo

BACKGROUND Image-guided radiotherapy used multiple imaging during the radiation therapy course to improve the precision and accuracy of health care provider's treatment. OBJECTIVES This study aims to assess the safety, effectiveness and economic aspects of image-guided radiation therapy for decision-making about this technology in Iran. METHODS In this study, the most important medical data...

Journal: :Laryngo-rhino-otologie 2022

CUP syndrome (cancer of unknown primary) describes the presence histologically proven metastases in an primary tumor. It affects about 3–5% all tumor patients. The search for makes extensive diagnostics necessary. However, 2/3 patients original is not discovered. Operation, radiation, chemotherapy and, some cases, targeted therapy are available as treatment. prognosis unfavorable.

2010
Vedang Murthy Sayan Kundu Tanweer Shahid Ashwini Budrukkar Tejpal Gupta Sarbani Ghosh Laskar Jaiprakash Agarwal

Though early stage head and neck cancers can be cured either by surgery or radiation, patients with locally advanced disease continues to pose a therapeutic challenge. Locoregional failure is the major cause of death in head and neck cancers. As the outcome of locally advanced head and neck cancer is less than promising, a combined modality approach is generally undertaken in this group of pati...

Journal: :Der Gynäkologe 2009

Journal: :Chang Gung medical journal 2004
Ming-Shian Kao

Management of recurrent endometrial carcinoma has traditionally focused on providing targeted adjuvant therapy in select groups of patients based on their risk factors. Major progress has been made over the last two decades in identifying these clinical-pathological risk factors, which has led to the classification of patients into different risk groups. Patients with high-risk factors are gene...

Journal: :Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006
Jeffrey Y C Wong An Liu Timothy Schultheiss Leslie Popplewell Anthony Stein Joseph Rosenthal Mark Essensten Stephen Forman George Somlo

Total body irradiation (TBI) is an important part of bone marrow transplantation conditioning regimens. In TBI, dose escalation is difficult, because of associated normal organ toxicities. A method to deliver a more targeted dose of TBI preferentially to sites of greatest tumor burden is needed to reduce the dose to normal organs, reduce toxicities, and permit dose escalation. The purpose of th...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Paul Okunieff Lisa A Kachnic Louis S Constine Clifton D Fuller Laurie E Gaspar Daniel F Hayes Jean Hooks Clifton Ling Frank L Meyskens Philip A Philip David Raben Stephen R Smalley Gregory P Swanson Beverly A Teicher Charles R Thomas Bhadrasain Vikram Michael J Zelefsky Laurence H Baker

Strategic planning for the Radiation Therapy Committee of the Southwest Oncology Group (SWOG) is comprehensively evaluated every six years in an effort to maintain a current and relevant scientific focus, and to provide a standard platform for future development of protocol concepts. Participants in the 2008 Strategic Planning Workshop included clinical trial experts from multiple specialties, ...

2017
Stephanie M Yoon Talha Shaikh Mark Hallman

Lung cancer is the leading cause of cancer death worldwide. Majority of newly diagnosed lung cancers are non-small cell lung cancer (NSCLC), of which up to half are considered locally advanced at the time of diagnosis. Patients with locally advanced stage III NSCLC consists of a heterogeneous population, making management for these patients complex. Surgery has long been the preferred local tre...

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