Technetium-99m-antimony trisulfide colloid ((99m)Tc-ATC) was investigated with varying specific activity in the rat lymphatic system, as well as its binding to rat blood cells in vitro. Low, moderate and high doses of (99m)Tc-ATC were subdermally injected into tails of rats (n=3) and 30min later whole body lymphoscintigraphic images were acquired. (99m)Tc-ATC was incubated for 30min at 37°C wit...

AIM Various studies have been conducted for determining the most optimal method for the early diagnosis of local recurrent or distant metastatic thyroid cancers. The aim of this study was to evaluate the clinical utility of technetium-99m (Tc-99m)-labeled octreotide derivatives in the detection of recurrence or distant metastases in medullary thyroid cancer patients and to compare the lesions w...

Introduction:Diethylenetriaminepentaacetic acid (DTPA) is a chelating agent used as a radiopharmaceutical compound, 99mTc-DTPA, for renography. Doxorubicin (DOX) on the other hand is an effective chemotherapy drug used to treat a variety of solid malignancies.  Both 99mTc-DTPA and DOX may be used in close succession in patients undergoing DOX based chemoth...

UNLABELLED In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotracer based on the aspartic-N-monoacetic acid (ASMA) ligand, (99m)Tc(CO)(3)(ASMA). The ASMA ligand features 2 carboxyl groups and...

UNLABELLED Early detection of heart disease is essential for the implementation of intervention strategies that reduce the risk of cardiovascular events. Radioimaging methods that have been explored for this purpose include (18)F-FDG, which measures sites of elevated metabolic activity; (99m)Tc-annexin A5, which reveals regions of enhanced apoptosis and thrombosis; and (99m)Tc-labeled anti-lect...

  Introduction: Ubiquicidin (UBI) 29-41 is a synthetic antimicrobial peptide that binds with the microbial cell membrane at the location of infection. This study was conducted to evaluate its probable efficacy as an infection-imaging agent with potential to differentiate bacterial infection from sterile inflammation in humans. Methods: Fifteen diabetic foot patients ...

Tc-99m-MIBI is an isonrtrile derivative used for evaluation of myocardial perfusion in recent years. In this preliminary report, 7 patients with coronary artery disease are evaluated with Tc-99m-MlBl stress planar and sped studies. Good correlation with coronary angiography is observed in these cases. In view of inherent technical problems present with thallium 201, Tc-99m-MIBi is a good ...

bilateral diffuse intense breast uptake was noted in a 40 year old female who was evaluated with tc-99m sestamibi (mibi) myocardial perfusion scan for possible ischemia. she was breast feeding her 1.5 year old child. the intense uptake in the breasts was superimposed on the apical and anteroapical regions of the myocardium and caused interpretation problem. we recommend considering tc-99m mibi ...

introduction: many radiotracers have been used for sentinel node mapping with acceptable results. the main difference between these radiotracers is the particle size. in the current study, we reported defective labeling of tc-99m antimony sulfide colloid which resulted in large particle size. methods: tc-99m-antimony sulfide colloid was used for axillary sentinel node mapping of 45 breast cance...

introduction: several radiotracers are being used for sentinel node mapping in patients with breast cancer. in the current study, we reported our experience with 99m-tc phytate for sentinel node mapping in mashhad university of medical sciences. methods: all breast cancer patients who underwent sentinel node mapping using 99m-tc phytate were included. all patients received intradermal peri-areo...