50 years ago (1958) The Rappaport Classification system for lymphomas had recently been introduced (1957). In that scheme, lymphomas were considered either nodular or diffuse and either well differentiated, poorly differentiated, undifferentiated, or mixed. The term histiocytic was introduced based upon the belief that neoplasms of large cells were derived from non-lymphoid cells. It is likely ...

Management of recurrent glioblastoma multiforme (GBM) remains a challenge. Several institutions reported that a single fraction of ≥ 20 Gy for small tumor burden results in excellent local control; however, this is at the expense of a high incidence of radiation necrosis (RN). Therefore, we developed a hypofractionation pattern of 33 Gy/3 fractions, which is a radiobiological equivalent of 20 G...

Cutaneous lymphomas are particularly radiosensitive and amenable to palliative radiation therapy. Total skin electron beam therapy (TSEB) is effective for palliation of Sézary syndrome and cutaneous T-cell lymphoma with large body surface area involvement. Focal radiation therapy is often used for treatment of localized disease. Treatment of cutaneous T-cell lymphoma can often pose technical ch...

JANUARY/FEBRUARY 2008 I RETINA TODAY I 41 T he management of retinoblastoma has gradually evolved over the years from enucleation to radiotherapy to current techniques of chemotherapy. Eyes with massive retinoblastoma filling the globe are still managed with enucleation, whereas those with small, medium, or even large tumors can be managed with chemoreduction followed by tumor consolidation wit...

BACKGROUND To quantitatively evaluate radiation-induced impaired oesophageal transit with oesophageal transit scintigraphy and to assess the relationships between acute oesophagitis symptoms and dysmotility. METHODS Between January 1996 and November 1998, 11 patients affected by non-small-cell carcinoma of the lung not directly involving the oesophagus, requiring adjuvant external beam radiot...

BACKGROUND Metastatic bone disease is found in 80-90% of patients examined after death and is a serious problem in everyday practice. The aim of the study was the evaluation of the survival time of patients with bone metastases in relation to the prognostic group and applied treatment. MATERIAL AND METHODS The authors analyzed 84 patients treated in the Radiotherapy Division of Lower Silesian...

PURPOSE To discuss the issue of screening for prostate cancer in elderly individuals. The impact of life expectancy on the choice of treatment in both patients and health care providers has been investigated as well. MATERIALS AND METHODS We identified studies published from 1990 onwards by searching the MEDLINE database of the National Library of Medicine. Initial search terms were "localize...

Fifty-three patients with biochemical relapse (BCR) after receiving external beam radiotherapy (EBRT) against locally advanced prostate cancer (stage III : International Union Against Cancer [UICC] 6th edition) between September 1997 and January 2006 at our institution, who were treated with salvage hormonal therapy (HTx), were followed for a mean period of 75.5 months. There was progression to...

PURPOSE Palliation of dysphagia is a challenge in advanced esophageal cancer. The addition of external beam radiotherapy (EBRT) to intraluminal brachytherapy (ILBT) has shown significant improvement in dysphagia relief and symptom scores. The aim of the present study was to evaluate the efficacy of combined use of ILBT and EBRT. MATERIAL AND METHODS The medical records of 148 patients with ad...

Adjuvant radiotherapy is recommended post breast conserving surgery. Accelerated Partial Breast Irradiation (APBI) offers a more attractive shorter course of treatment over 5 days compared to standard conventional external beam radiotherapy, which is often protracted. Multi-catheter interstitial APBI offers excellent dosimetric coverage. This article describes two insertion techniques for multi...