Trimethyltin (TMT) is an organotin compound with potent neurotoxic effects characterized by neuronal destruction in selective regions, including the hippocampus. Glycogen synthase kinase-3 (GSK-3) regulates many cellular processes, and is implicated in several neurodegenerative disorders. In this study, we evaluated the therapeutic effect of lithium, a selective GSK-3 inhibitor, on the hippocam...

BACKGROUND Customer capital is a value generated and an asset developed from customer relationships. Successfully managing these relationships is enhanced by knowledge management (KM) infrastructure that captures and transfers customer-related knowledge. The execution of such a system relies on the vision and determination of the top management team (TMT). The health care industry in today's kn...

Upper echelon theory (UET) emphsizes the role of management in determining firm strategy that can lead to performance. Many studies have been conducted on UET but very few addressed international business research, especially halal industry. Implementing learning orientation as a culture serve medium transferring tacit knowledge within firm. Therefore, this research was examine mediating effect...

According to terror management theory, people turn to meaning-providing structures to cope with the knowledge of inevitable mortality. Recent theory and research suggest that nostalgia serves such an existential function by supplying a reservoir of meaningful life experiences which can be used as a defense against death concerns. The current research tests and supports this idea. In Experiments...

According to amoebic self theory, the boundary defining the self encompasses 3 levels of self-representation--bodily, social, and spatial-symbolic. Study 1 related a newly developed measure of individual differences in sensitivity to boundary threat across these 3 domains to values and disgust sensitivity. Four subsequent studies focused on spatial-symbolic threat sensitivity and related it to ...

Terror management theory emphasizes that self-esteem consists of a sense of meaning and significance, which serves mainly to defend against death awareness. The current authors counter that people's search for meaning and significance cannot be wholly reduced to defensive processes because it also reflects intrinsic developmental processes. Sociometer theory similarly offers a mainly defensive ...

We examine the effect of top management team (TMT) professional finance experience on firm investment efficiency. Top managers with a career background in help reduce deviations from level warranted by fundamentals. Reductions inefficiencies are achieved financial expert using project-specific rather than company-wide, discount rates for project evaluation and facilitating debt equity issuance ...

Abstract Leveraging the human capital specificity and Chief Executive Officer (CEO)–top management team (TMT) interface literature, this study explores impact of generalist versus specialist CEOs on R&D commitments by Indian firms under boundary conditions TMTs' functional educational diversity. Based a sample 253 over period 6 years, in contrast to previous studies, our findings suggest th...