A novel mass spectrometry-based methodology using electrospray ionization (ESI) is described for the detection of protein-protein [interferon (IFN)-γ dimer] and protein-ligand [ras-guanosine diphosphate (GDP)] noncovalent interactions. The method utilizes ESI from aqueous solution at appropriate pH. The presence of the noncovalent complex of the IFN-γ dimer was confirmed by the observed average...

Parallel le systems employ data declustering to increase I/O throughput. As a result, a single read or write operation can generate concurrent data accesses on multiple storage devices. Unless a concurrency control mechanism is employed, familiar le access semantics are likely to be violated. This paper details the transaction-based concurrency control mechanism implemented in the PIOUS paralle...

We define and analyze the ACATS declustering scheme for use with the classic Level 5 as well as MDS RAIDs. ACATS provides a paradigm for distributed sparing and checking as well. Using Markov models we calculate the reliability of classic Level 5 as well as MDS RAIDs both with and without ACATS. Our results demonstrate, for fixed hardware configurations, tradeoffs between performance and reliab...

We consider a variant of graph developing system and show various behavior with one type of graph-rewriting. This system is based on rewriting of 3-regular graphs with two possible states per node. We focus on a simple case of fixed number of nodes. The development processes include interaction among rather stable subgraphs. Some simple behaviors, such as clustering and declustering of states, ...

Clustered multimedia servers, consisting of interconnected nodes and disks, have been proposed for large scale servers, that are capable of supporting multiple concurrent streams which access the video objects stored in the server. As the number of disks and nodes in the cluster increases, so does the probability of a failure. With data striped across all disks in a cluster, the failure of a si...

Intra-query parallelism is important for achieving high performance in parallel processing environment. For processing a signatrue file in parallel, an effective declustering algon’thm that must avoid data skew and execution skew is needed. The Linear Code Decomposition Method(LCDM) that is used for the Hamming filter may give a good performance, but it fails to evenly decluster a signature fil...