Smoking induces mutations via the formation of DNA-adducts in the bronchial and alveolar epithelium and contributes to the development of lung cancer. Benz(a)pyrene and nitrosamine, typical carcinogens in cigarette smoke, undergo metabolic activation by the phase I enzymes, such as cytochrome P450 (CYP) 1A1, CYP2A6 and CYP2E1. The transcriptional regulation of these phase I enzymes is regulated...

OBJECTIVES This study compares the long-term performance of the Carpentier-Edwards (CE) porcine bioprosthesis and the CE pericardial bioprosthesis for aortic valve replacement (AVR). BACKGROUND With new bioprostheses on the horizon, there is renewed interest in how the long-term durability of current pericardial bioprostheses compares with the traditional porcine bioprosthesis. METHODS We r...

Brandeis University, Waltham, MA 02454 9 10 11 12 13 14 15 Running title: Activity regulates PSD-95-mediated synaptic strengthening 16 17 Correspondence: John E. Lisman 18 Biology Department and Volen Center for Complex Systems 19 Brandeis University, Waltham, MA 02454 20 E-mail: [email protected] 21 Phone: 781-736-3145 22 Fax: 781-736-3107 23 24 25 Articles in PresS. J Neurophysiol (November...

background: routine diagnostic methods of vesicoureteral reflux (vur) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. the objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...

KP-736, a new cephen antibiotic with a broad antibacterial spectrum and potent antipseudomonal activity, was evaluated for in vitro antibacterial activity in comparison with ceftazidime, cefotaxime, and cefpirome. KP-736 was significantly more active than the test compounds against gram-negative bacteria, including the Pseudomonas group and ceftazidime-, cefotaxime-, or imipenem-resistant strai...

BACKGROUND Anastomosing hemangioma (AH) is a very rare vascular tumor mimicking angiosarcoma, predominately observed in kidney and less frequently in other organs. We present two new renal cases of AH at opposite ends of the clinical presentation spectrum, provide review of the literature and compare the epidemiological, clinical and pathological profiles of renal and non-renal cases. CASE PR...

Proof. First suppose that a ∼H b, so that a = bk for some k ∈ H, and let ah (with h ∈ H) be an artibrary element of aH. Then we have ah = bkh = b(kh) ∈ bH, hence aH ⊆ bH. The proof of bH ⊆ aH is similar. Conversely, suppose that aH = bH. Since a ∈ aH = bH we have a = bk for some k ∈ H. Then a−1b = k−1 ∈ H, hence a ∼H b. (d) Prove that the map g 7→ ag is a bijection from H to aH. Proof. Consider...

PURPOSE To analyze the anatomic consequences of selective amygdalohippocampectomy (AH) in patients with hippocampal sclerosis and to correlate the clinical outcome with the MR appearance. METHODS Seventeen patients were examined with clinical and neuropsychologic examination and cranial MR after AH (7 transcortical AH, 10 trans-Sylvian AH). The clinical and neuropsychologic outcomes after AH ...