Peroxisome proliferator-activated receptors (PPARs) play an important role in regulating both glucose and lipid metabolism. Agonists for both PPARgamma and PPARgamma have been used to treat dyslipidemia and hyperglycemia, respectively. In addition to affecting glucose metabolism, PPARgamma agonists also regulate lipid metabolism. In this review, we will focus on the randomized clinical trials t...

Although the highest levels of PPARgamma expression in the body have been reported in the gastrointestinal epithelium, little is known about the physiological functions of that receptor in the gut. Moreover, there is considerable controversy concerning the effects of thiazolidinedione PPARgamma agonists on the two major diseases of the gastrointestinal track: colorectal cancer and inflammatory ...

In today’s modern world depression has become a common stress factor among both men and women irrespective of age. But to be specific, it been found that there is strong relationship between diabetes depression. The rate this seems higher much literature suggests us the numbers could increasing in future. Depression may arise due some factors such as comorbidities, improper management blood glu...