Betel quid use and abuse is wide spread in Asia but the physiological basis of intoxication and addiction are unknown. In subjects naïve to the habit of betel quid intoxication, the psychological and physiological profile of intoxication has never been reported. We compared the effect of chewing gum or chewing betel quid, and subsequent betel quid intoxication, on psychological assessment, pros...

PURPOSE The authors' laboratory has previously documented formate-induced retinal toxicity in a rodent model of methanol intoxication. These studies determined functional, bioenergetic, and structural recovery of the retina after methanol intoxication. METHODS Rats were intoxicated with methanol, and retinal function was assessed by electroretinography 72 hours after the initial dose of metha...

AIMS We investigated if increased drinking frequency among adults in the second half of life co-occurred with increased usual quantity and increased intoxication frequency. DESIGN Two-wave panel study. SETTING Norway. PARTICIPANTS Norwegian adults (1017 women and 959 men) aged 40-79 years. MEASUREMENTS Drinking frequency, usual quantity and intoxication frequency was measured by self-re...

In a large case-control study (n = 1,926) of spontaneous abortion (SAB), exposure to solvents was ascertained by a telephone interview that asked about occupational use of 18 specific solvents or products, as well as an open-ended "other" solvent category. The adjusted odds ratio for use of any solvent was 1.1 (0.8, 1.5). Solvents for which at least a doubled crude risk of SAB was found include...

The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, cardiac=20 mg/l) 40-fold higher than the usual treatment concentration, and si...

Conclusions: Amanita phalloides intoxication can be successfully treated with N-acetylcysteine in addition to the standard regimen. Significantly, the simplicity of administration, good tolerance, and an affordable cost make N-acetylcysteine a viable option for the treatment of Amanita phalloides intoxication. The low mortality rate presented in the study group may be ascribed to N-acetylcystei...

KEY CLINICAL MESSAGE In-hospital hanging during a confusional state from alcohol intoxication is rare. To treat cases of acute alcohol intoxication, careful observation will be needed to avoid accidental psychological reactions.

Introduction: Deep heated oils produce toxins that endanger people's health. The current study aims to investigate the simultaneous effect of aerobic training and Octopamine consumption on the mitophagy of brown adipose tissue after the induction of intoxication through deeply heated oil in male wistar rats. Method: 40 male wistar rats after four weeks of feedi...

We analyze the interaction of black-white race with physical and socioeconomic characteristics in the US marriage market, using data from the Panel Study of Income Dynamics. We estimate who inter-racially marries whom along anthropometric and socioeconomic characteristics dimensions. The black women who inter-marry are the thinner and more educated in their group; instead, white women are the f...