It was studied in Antarctic fishes the anesthetic and/or analgesic actions of central depressors ketamine, fentanyl and thiopental as well as the local anesthetic benzocaine. The drugs were added to aerated marine water at temperatures of 1-1.5 C. Ketamine (15 mg/L) and fentanyl (50 g/L) failed in inducing anesthesia but caused a long lasting analgesia and sedation. Thiopental was required in d...

Two novel polymeric membrane sensors for the analysis of Pb(II) have been developed based on two therapeutic drugs, thiopental (TP) and phenytoin (PT) as two new ionophores and potassium tetrakis(p-chlorophenyl) borate (KTpClPB) as a lipophilic additive, in plasticized PVC membranes. The sensors show a Nernstian response for Pb(II) ions over the wide concentration ranges of 1×10(-2) - 7×10(-6) ...

We compare a new ultrafiltration technique, involving a unique Millipore membrane, with the classical method of equilibrium dialysis for determining the fraction of thiopental not bound to serum proteins. This fraction, as determined by equilibrium dialysis at 37 degrees C, ranged between 12 and 16% for total concentrations at 50 microgram/L to 10 mg/L of serum. In contrast, ultrafiltration at ...

laryngeal mask is a supraglothic instrument for ventilation of patients who are under anesthesia. insertion of laryngeal mask requires maintaining sufficient depth of anesthesia to avoid airway reflex (gagging, coughing and spasms). the present study investigated two techniques of anesthesia with propofol-atracurium and thiopental-atracurium to facilitate insertion of the laryngeal mask, term o...

rabbits are widely used as laboratory animals for experimental surgery. anesthesia of rabbits may present complications unless the method is easy to apply and safe to use. in present study, effects of different dosages of vitamin c on thiopental sodium induced anesthesia in 25 male new zealand white rabbits were studied. in the animals that had not received vitamin c treatment before thiopental...

background:   objective: this study aimed at investigating the side effects and hemodynamic effects of using thiopental sodium and propofal as well as effects of these drugs on pregnancy outcome in art cycles.   materials and methods: in this double blinded) randomized controlled trial, 90 woman candidate for art were randomly divided into two groups. 47 patients received propofol (2.5 mg/kg) a...

both midazolam and thiopental sodium are being used as induction agents and for maintenance of anesthesia. in contrast to other benzodiazepines such as diazepam, midazolam has a rapid onset of action and fast distribution and causes few cardiovascular or respiratory effects. being water soluble, midazolam is also associated with a low incidence of venous irritation. the purpose of this study wa...

We describe a system for monitoring and controlling i.v. anaesthesia in rats using burst suppression ratio (BSR) detection in the extradural EEG. After bolus injection, peak BSR values of 95% were achieved with propofol 8 mg kg-1, etomidate 3.5 mg kg-1 and alphaxalone 4.5 mg kg-1. Thiopental 32 mg kg-1 produced a peak BSR of 70% (larger doses were not tolerated). Recovery was fastest with propo...

1 Zand F, Hadavi SMR, Chohedri A, Sabetian P. Survey on the adequacy of depth of anaesthesia with bispectral index and isolated forearm technique in elective Caesarean section under general anaesthesia with sevoflurane. Br J Anaesth 2014; 112: 871–8 2 Tunstall ME. The reduction of amnesic wakefulness during caesarean section. Anaesthesia 1979; 34: 316–9 3 Russell IF. The ability of bispectral i...