The research described in this Thesis is part of a project to develop a new database system for proteo-chemometric research. This new system uses a mediator/wrapper approach for integrating heterogeneous and autonomous data sources. Special-purpose modules for data representation and data analysis can be incorporated into the system through the extensibility of the object-relational mediator. L...

This article is the second in a series that lists four key explanatory or tutorial references for each of 29 chemometric methods previously described. The selected are particularly helpful to explain use method spectroscopic data. Also included common computer software platforms used chemometrics.

The cumulative particle size distribution of microcrystalline cellulose, a widely used pharmaceutical excipient, was determined using near infrared (NIR) reflectance spectroscopy. Forward angle laser light scattering measurements were used to provide reference particle size values corresponding to different quantiles and then used to calibrate the NIR data. Two different chemometric methods, th...