BACKGROUND Polybrominated diphenyl ether (PBDE) flame retardants have been implicated as disruptors of the hypothalamic-pituitary-thyroid axis. Animals exposed to PBDEs may show reduced plasma thyroid hormone (TH), but it is not known whether PBDEs impact TH-regulated pathways in target tissues. OBJECTIVE We examined the effects of dietary exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE-...

Vol. 30, No. 1, 2018 125 Received December 14, 2016, Revised March 6, 2017, Accepted for publication March 10, 2017 Corresponding author: Agnethe Berglund, Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus, Denmark. Tel: 45-78-45-00-00, Fax: 45-78-46-20-10, E-mail: agnetheberglund@ dadlnet.dk This is an Open Access article distributed...

The aim of the present study was to investigate the prevalence of antipituitary antibodies (APA) in patients with autoimmune thyroid disease as determined by Western blot analysis and enzyme-linked immunosorbent assay (ELISA). Results by Western blot analysis showed positivity for APA in serum of 22.4% of patients with Graves' disease (n= 143, p<0.05) and 18.5% of patients with Hashimoto's thyr...

OBJECTIVE: This study was carried out to determine the serum metabolite antioxidants concentration(Vitamins C and E and other cofactors such as zinc and iron) serving as indicesand correlated with the anti-microsomal antibody level, which is one of the markers and causes of infertility

Autoimmune thyroid diseases (AITD), which include Hashimoto thyroiditis (HT), Graves' disease (GD) and primary idiopathic myxoedema (PIM), are recognized by their clinical and genetic heterogeneity. In this study, we have carried on a global approach gathering 20 year genetic and clinical data on a Tunisian multigenerational family (Akr). Our purpose was search for a combined genotype involved ...

We are indebted to Dr Rita H. Cornforth of the National Institute for Medical Research for the synthesis of [2-14C]mevalonic acid; to Professor A. Wormall, F.R.S., for a gift ofsqualene and to Horlicks Ltd. for a supply of ,B-mercaptoethylamine (Becaptan). The spectroscopic examination of the microsomes were done by Dr F. A. Holton. It is a pleasure to acknowledge the skilled technical assistan...

INTRODUCTION Despite long standing iodine supplementation in Iran the prevalence of goiter remains high in some areas. This may suggest that causes other than iodine deficiency, such as autoimmune thyroid diseases, should also be considered. We therefore assessed the prevalence of anti-thyroid antibodies in children living in an inland area in Iran and correlated these findings with prevalence ...

a question upon which much attention has recently been directed. "While it is not yet fully established that organic disease can originate in this way, it is quite certain that very grave functional disturbances may be produced. When the complex processes of metabolism are perfectly performed, and at the same time there is efficient elimination of waste products, then auto-intoxication will not...

rfid technology has great potential to improve the benefits of supply chain management. auto- manufacturing is a competitive industry that every player of it needs great operation efficiency to gain competitive advantage to survive. rfid systems are good enhancements to supply chain processes, therefore it's obvious that every industry has to pay great attention to this it solution, and in this...