OBJECTIVE Recently, it has been questioned whether insulin resistance is associated with thyroid nodules. The aim of this study was to examine insulin resistance prevalence in a case-control study of patients with benign thyroid nodules in an iodine-sufficient area. METHODS This was a single-center, case-control study on euthyroid patients with benign nodular diseases. Thirty newly diagnosed ...

OBJECTIVE This study investigated the detection of thyroid nodule calcifications on ultrasound and their relationship to thyroid carcinoma. METHODS Microcalcifications (≤2 mm) and macro calcifications (>2 mm) on preoperative ultrasound examination of thyroid and lymph nodes were compared with postoperative pathological diagnoses in 4186 patients undergoing thyroid surgery. RESULTS Higher in...

We report the case of a 74-year-old man with a four-year history of right nephrectomy for clear cell renal carcinoma (CCRC) who was diagnosed with hyperthyroidism. On ultrasound (US), a 5 cm solid isohypoechoic nodule with intranodular vascularization was found in the left thyroid lobe. The nodule was deemed autonomous on (99m)Tc thyroid scan. Methimazole was started and serum thyroid hormone l...

A teenage girl had been diagnosed with Hashimoto’s thyroiditis and a thyroid nodule about 2 years ago. She has a family history of autoimmune thyroid disease, and a grandmother also had a goiter. Her thyroid function was normal on presentation. A neck ultrasound revealed a 3-cm nodule Fine-needle aspiration under ultrasound guidance was performed and cytology was consistent with follicular lesi...

N Eng J Med 2004;351:1764-71. Copyright © 2004 Massachusetts Medical Society. A 42-year-old woman presents with a palpable mass on the left side of her neck. She has no neck pain and no symptoms of thyroid dysfunction. Physical examination reveals a solitary, mobile thyroid nodule, 2 cm by 3 cm, without lymphadenopathy. The patient has no family history of thyroid disease and no history of exte...

Thyroid nodule prevalence is about 1.8% in healthy children; however, malignancy frequency is higher than in adults. Approximately 26.4% of thyroid nodules generate thyroid cancer in childhood. Coexisting thyroid disease, history of irradiation of the neck, post-pubertal age, female sex, and thyroid malignancy in the family are risk factors for developing nodules. After evaluation of the medica...

OBJECTIVE The aim of this study was to evaluate and compare the efficacy of single-treatment cooled and uncooled microwave ablation in thyroid nodules. METHODS Eighteen patients (11 women) with an average age of 62 years (range: 41-80) with 18 cold, mainly solid or solid thyroid nodules were treated with cooled or uncooled microwave ablation. Pain during the treatment was measured on a 10-poi...

The combination of autoimmune Graves’ disease with a solitary hot thyroid nodule suppressing the remainder of the thyroid gland is rare. We report a case of Graves’ disease associated with a single hyperfunctioning nodule with suppression of the remaining gland. A 45 year old male patient with past medical history of autoimmune Graves’ disease with severe ophthalmopathy was referred to endocrin...

SURGERY IN SIMPLE GOITRE The Solitary Nodule The apparently solitary swelling, clinically and colloquially referred to as a ' simple adenoma,' may histologically be a hyperplastic nodule (due to compensatory hyperplasia) or a neoplastic nodule (innocent or malignant). The management of the solitary nodule is influenced in some hands by the availability or not of 131I facilities for investigatio...

Introduction: Thyroid nodules are a common clinical entity found among the adult general population. With increasing use of imaging investigations like ultrasonography, there has been a significant rise in the detection of non-palpable thyroid nodules that require further evaluation and management. The routine use of FNAC has reduced the number of unnecessary surgical procedures for thyroid nod...