OBJECTIVES We assessed the analytical performance of the TSH and FT4 assays on ADVIA Centaur in a multicenter national evaluation. DESIGN AND METHODS A precision study and a method comparison were performed. Reference values stated by the manufacturer were checked from 379 normal subjects. RESULTS For TSH and FT4, the intra-assay CVs were below 2.3 and 5.2%, respectively, and the inter-assa...

We evaluated four new nonisotopic immunoassays of free thyroxin (FT4)--Amerlite FT4 (Amersham International), Magic Lite FT4 (Ciba Corning Diagnostics), Stratus FT4 (Dade--Baxter Travenol), and FT4 Enzelsa (Compagnie ORIS Industrie)--by comparison with two FT4 radioimmunoassays: Amerlex and Sclavo. Inter- and intra-assay coefficients of variation were less than 10% in the working range and ther...

BACKGROUND The aim of this study was to evaluate the non-genomic action of thyroxin on sperm kinetic and its probable use to improve sperm recovery after applying an en- richment method like "swim-up" in comparison with the available one, pentoxifylline. MATERIALS AND METHODS This is an experimental study. A total of 50 patients were re- cruited, followed by infertility consultation. Conventi...

AIMS We examined effects of treatment with 1-thyroxin on glucose regulation in patients with subclinical hypothyroidism. METHODS The study included 100 patients, ages 51.75 +/- 13.23 years, BMI = 27.97 +/- 4.52 kg/m2, with SH (TSH > 4.2 mU/L and with normal level of T3 and T4). Laboratory evaluation included serum free T3, free T4, TSH, thyroid antibodies, TGL, insulin, C-peptide and glucose ...