BACKGROUND Traditional tibial nerve stimulation (TNS) has been used to treat overactive bladder syndrome (OAB), but there are some shortcomings. Thus, a novel alternative is needed for the treatment of OAB. The study investigated the effects of a new type of tibial nerve microstimulator on the micturition reflex in cats. METHODS An implantable wireless driver microstimulator was implanted aro...

The purpose of this study was to evaluate the inter-hamstring position (medial to lateral intertendinous position) of the tibial nerve within the popliteal fossa. A descriptive cadaver model study was performed to permit controlled and direct measures of the tibial nerve. Fourteen embalmed lower extremities (8 left, 6 right) from nine cadavers (4 males, 5 females; 84.3 +/- 10.7 years of age) we...

The present study was performed to investigate the effects of long-term intraperitoneal (IP) injection of vitamin B12 and diclofenac in separate and combined treatments on cold and mechanical allodynia in a neuropathic pain model in rats. Neuropathic pain was induced by crush injury in right tibial nerve. Acetone spray and von Frey tests were used to obtain cold and mechanical allodynia respons...

The present study was performed to investigate the possibility of "aberrant" innervation of the tips of the hindlimb digits in the rat, i.e., from other sources than the femoral and the main sciatic branches (tibial, peroneal, sural). Cutaneous injections of fluorescent tracers in the digits were combined with either selective nerve transections to restrict afferent routes followed by detection...

Nerve Injury In article 2200227, Jingwei Xie and co-workers summarize the recent advances in microfluidic nerve injury models, which enable scientists to test various hypotheses regeneration mechanisms. Representative device designs techniques, such as vacuum-assisted axotomy, compression or tension-based physical injury, laser-based chemical are described discussed.

OBJECTIVE To compare nerve conduction parameters in asymptomatic diabetic patients and with no clinical signs of neuropathy and in control subjects. METHODS Forty-eight diabetic Saudi subjects (20 males, 28 females) and 48 age-and-sex-matched control subjects were studied. The mean age of patients +/- standard deviation was 45.6+/-11.7 years. The mean duration of diabetes from time of diagnos...

background suprascapular neuropathy (ssn) is generally thought of as a diagnosis of exclusion. however, increasing attention is being paid to the diagnosis, treatment and rehabilitation of this pathology to prevent chronic supraspinatus and infraspinatus atrophy in patients. to date, literature has only articulated variable or customized treatment and rehabilitation plans without clear standard...

The tibial nerve transection model is a well-tolerated, validated, and reproducible model of denervation-induced skeletal muscle atrophy in rodents. Although originally developed and used extensively in the rat due to its larger size, the tibial nerve in mice is big enough that it can be easily manipulated with either crush or transection, leaving the peroneal and sural nerve branches of the sc...

The development of fecal incontinence after childbirth is a common event. This incontinence responds to a multifactorial etiology in which the most common element is external anal sphincter injury. There are several risk factors, and it is very important to know and avoid them. Sphincter injury may result from perineal tear or sometimes by incorrectly performing an episiotomy. It is very import...