BACKGROUND No-reflow (TIMI < 3) during primary PCI (PCI) for STEMI occurs in 11-41% of cases, indicates poor myocardial tissue perfusion, and is associated with a poor outcome. We aimed to determine predictors and 12 month outcomes of patients who developed no-reflow. METHODS We analysed the PCI database of The Canberra Hospital and identified 781 patients who underwent primary PCI during 200...

In addition to hypercholesterolemia, chronic arterial inflammation has been shown to be strongly associated with atherosclerosis and cardiovascular disease (CVD) [1]. The accumulation and oxidation of LDL within the intima trigger inflammatory processes within the vessel wall. Certain markers of inflammation, such as C-reactive protein (CRP), soluble CD40 ligand (sCD40L), oxidized LDL, and lipo...

OBJECTIVES To evaluate the effect of vascular complications (VC) on the adjusted risk of nonfatal myocardial infarction (MI) or death following percutaneous coronary intervention (PCI) at 1 year in a large contemporary cohort. BACKGROUND Peri-procedural bleeding increases the risk of adverse clinical outcomes at 1 year. Whether access site VC's identify patients at high risk or independently ...

STUDY OBJECTIVE Coronary computed tomographic (CT) angiography has excellent performance characteristics relative to coronary angiography and exercise or pharmacologic stress testing. We hypothesize that coronary CT angiography can identify a cohort of emergency department (ED) patients with a potential acute coronary syndrome who can be safely discharged with a less than 1% risk of 30-day card...

BACKGROUND AND PURPOSE Data from recent reports have indicated that mechanical thrombectomy may have potential as a treatment for acute ischemic stroke. The purpose of this study was to assess the safety and performance of the Penumbra System (PS): a novel mechanical device designed to reduce clot burden in acute stroke due to large-vessel occlusive disease. MATERIALS AND METHODS A prospectiv...

Three patients with internal carotid artery thrombus and thrombolysis in myocardial infarction (TIMI) 0-1 flow were treated by using intraarterial (IA) suction thrombectomy a mean of 4.2 hours after stroke onset. After catheterization with a 7F guide-catheter, thrombus was aspirated by using a 60-mL syringe. TIMI flow improved to 3 in all patients. The median National Institutes of Health Strok...