The way that progenitor cell fate decisions and the associated environmental sensing are regulated to ensure robustness of spatial temporal order in which cells generated towards a fully differentiating tissue still remains elusive. Here, we investigate how regulate their intensity radius guarantee required thermodynamic differentiated tissue. In particular, interested finding conditions where ...

Three-dimensional engineering of skeletal muscle is becoming increasingly relevant for tissue engineering, disease modeling and bio-hybrid robotics, where flexible, versatile multidisciplinary approaches the evaluation differentiation, functionality force measurement are required. This works presents a 3D-printed platform bioengineered human which can efficiently model three-dimensional structu...

Tumours composed of different kinds of tissue show different characteristics in rate of growth, infiltration of surrounding structures, frequency of complications such as necrosis and haemorrhage, and development of metastases. Thus the prognosis, either natural or following treatment, of various neoplasms, differs. This applies obviously to tumours of different organs or structures, but is tru...