Three-dimensional (3D) bioprinting technology has emerged as a powerful bio- fabrication platform for tissue engineering because of its ability to engineer living cells and bio-material based 3D objects. Diverse bio-inks on synthetic natural biomaterials have also been created successfully used regeneration at the same time. Over past few decades, fields regenerative medicine, which aim develop...

Articular cartilage has poor healing ability and cartilage injuries often evolve to osteoarthritis. Cell-based strategies aiming to engineer cartilaginous tissue through the combination of biocompatible scaffolds and articular chondrocytes represent an alternative to standard surgical techniques. In this context, perfusion bioreactors have been introduced to enhance cellular access to oxygen an...

Although there is widespread recognition of the importance of angiogenesis in tissue repair, there is little work on the inhibition of angiogenesis in the context of tissue engineering of naturally avascular tissues, like articular cartilage. The objective was to engineer a collagen-scaffold-based cartilaginous construct overexpressing a potent antiangiogenic factor, endostatin, using nonviral ...

Abstract To date, the ultimate goal of bioprinting is to create autologous tissue grafts for future replacement therapies through utilization cells and biomaterials simultaneously. Bioprinting an additive manufacturing technology that has significant potential in biomedical field. Among main techniques, such as inkjet, laser extrusion bioprinting, laser-induced forward transfer technique (LIFT)...

stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been elusive dream in medical sciences and improvement of stem cell homing as one of major challenges in cell therapy programs, has been considered a promising milestone. it has been proved that stem/progenitor cells exhibit a homing response to injured tissues/organs, mediated by interactions of chemoki...