Immunological unresponsiveness or hyporesponsiveness (tolerance) can be induced by feeding protein antigens to naive animals. Using a classical oral ovalbumin gut-induced tolerance protocol in BALB/c mice we investigated the effects of dietary n-6 and n-3 polyunsaturated fatty acids (PUFA) on high-and low-dose oral tolerance (and in non-tolerised animals, i.e. effects of antigen challenge alone...

In this paper, an effective decision process method is proposed to address the challenge in a multiple criteria decision-making (MCDM) problem because of large number of criteria. This method is based on the criteria reduction, tolerance relation, and prospect theory (PT). By building a discernibility matrix for tolerance relation (DMTR) in an MCDM problem with numerical values or interval numb...

OBJECTIVE We evaluated the prevalence of glutamic acid decarboxylase (GADA) and tyrosine phosphatase-protein antibodies (IA2A), their titers and their relation to first phase insulin response (FPIR) and glucose tolerance in autoimmune thyroid diseases (ATDs) patients. SUBJECTS AND METHODS Graves' disease (GD; n = 181) and Hashimoto's thyroiditis (HT; n = 143) patients in addition to healthy c...

BACKGROUND Recent studies revealed an association between sleep disturbance and metabolic disorders, such as obesity and metabolic syndrome. An aim of this study was to assess the relation between sleep duration and diabetes mellitus in a representative sample of the Iranian population. MATERIALS AND METHODS Participants were 12514 individuals, (6123 men and 6391 women) studied in the baselin...