Pseudomonas cepacia G4 possesses a novel pathway of toluene catabolism that is shown to be responsible for the degradation of trichloroethylene (TCE). This pathway involves conversion of toluene via o-cresol to 3-methylcatechol. In order to determine the enzyme of toluene degradation that is responsible for TCE degradation, chemically induced mutants, blocked in the toluene ortho-monooxygenase ...

This study was undertaken to evaluate the influence of a carbohydrate restricted diet, a subacute ethanol intake, and their combined effect on the kinetics of toluene in humans. Eight healthy male volunteers were exposed by inhalation at four different occasions to 200 mg/m3 2H8-toluene for two hours at a work load of 50 W after a one week low (30%) carbohydrate (CH) diet or high (60%) CH diet ...

The Schiff base compounds N,N'-bis[(E)-quinoxalin-2-ylmethylidene]propane-1,3-diamine, C(21)H(18)N(6), (I), and N,N'-bis[(E)-quinoxalin-2-ylmethylidene]butane-1,4-diamine, C(22)H(20)N(6), (II), crystallize in the monoclinic crystal system. These molecules have crystallographically imposed symmetry. Compound (I) is located on a crystallographic twofold axis and (II) is located on an inversion ce...

The catalytic oxidation of toluene to benzoic acid in the liquid phase has been studied in an un-stirred tank reactor. Low concentration of acetic acid was added in order to increase the solubility of the catalyst in toluene. The dependence of the rate of reaction on the concentration of toluene catalyst and oxygen pressure was studied. It has been suggested that liquid phase oxidation of t...

Toluene is a major industrial solvent and substance of abuse which is ototoxic in rats as shown by both behavioral testing and measurement of brainstem auditory evoked response (BAER) thresholds. The objective of this investigation was to examine the morphological (hair cell loss) and functional (BAER threshold elevations) changes resulting from toluene administration. In the preliminary experi...

Toluene and o-xylene were completely mineralized to stoichiometric amounts of carbon dioxide, methane, and biomass by aquifer-derived microorganisms under strictly anaerobic conditions. The source of the inoculum was creosote-contaminated sediment from Pensacola, Fla. The adaptation periods before the onset of degradation were long (100 to 120 days for toluene degradation and 200 to 255 days fo...

Single-well, push-pull tests were conducted in a contaminated aquifer to evaluate the ability of toluene-oxidizing microorganisms to cometabolize chlorinated aliphatic hydrocarbons (CAHs), such as trichloroethene (TCE). Test solutions were injected into the aquifer using a standard monitoring well, and then were transported under natural-gradient conditions. Transport tests demonstrated similar...

Hydroxyl radical (OH) oxidation of toluene produces ring-retaining products: cresol and benzaldehyde, and ring-opening products: bicyclic intermediate compounds and epoxides. Here, firstand later-generation OH oxidation products from cresol and benzaldehyde are identified in laboratory chamber experiments. For benzaldehyde, first-generation ring-retaining products are identified, but later-gene...

The relationship between toluene concentration and the rate of leakage of solutes from toluene-treated roots and leaves of Sorghum bicolor, L. Moench, was studied to determine the effect of toluene on plant cell membranes. A threshold concentration of 0.2% toluene was needed to induce leakage. Maximal leakage rates were obtained with 0.5% toluene. Low molecular weight solutes, such as amino aci...