the main goal in endodontic treatment is to eradicate or at least reduce intraradicular microbial population to levels that are more compatible with periapical lesions healing process. since endodontic infections are polymicrobial in nature, intraradicular survival of endodontic microbiota and their pathogenic properties are influenced by a combination of their virulence factors. the purpose of...

We herein report a rare case of acute basophilic leukemia with t(16;21)(p11;q22) generating the FUS-ERG fusion gene. The basophilic nature of leukemia blasts was demonstrated by cytomorphology, toluidine blue metachromasia, mature basophil-associated antigen expression, and characteristic granules under electron microscopy. The molecular link between t(16;21)/FUS-ERG and basophilic differentiat...

Helicobacter pylori infection is associated with many gastroduodenal diseases such as peptic ulcer disease and gastric cancer (Uemura et al., 2001). The organism is the major cause of chronic active gastritis resulting in chronic atrophic gastritis and its end stage, gastric atrophy, which is believed to be a precancerous lesion (Pandey et al., 2010). Intestinal metaplasia, usually associated w...

Staphylococci are important causes of nosocomial and medical-device-related infections. Their virulence is attributed to the elaboration of biofilms that protect the organisms from immune system clearance and to increased resistance to phagocytosis and antibiotics. Photodynamic treatment (PDT) has been proposed as an alternative approach for the inactivation of bacteria in biofilms. In this stu...

Serum containing dextrans of average molecular weight 40,000 (“Dextran-40”), 70,000 (“Dextran-70”), or 75,000 (“Dextran-75”) become turbid when biuret reagent is added (1, ). This interference has been overcome (3) by first precipitating serum proteins with trichioroacetic acid before applying the biuret reaction. Positive interference of these drugs with the o-toluidine glucose assay has also ...

We recently noticed a significant error in the results for glucose determined by the o-toluidine method in qualitycontrol material prepared in our own laboratory. This interference was traced to one component of this control material, a uric acid stock solution containing formaldehyde. Uric acid has been reported to interfere (1, 2) and not interfere (3) in the o-toluidine procedure. The otolui...

Between 1982 and 1990 seven cases of bladder cancer were detected in a group of 49 workers who were synthesising chlordimeform from 4-chloro-o-toluidine. Latency periods ranged from 15 to 23 years. The incidence of bladder tumours in this group was significantly higher than that of the cancer registers of the former GDR, Saarland, and Denmark by factors of 89.7, 53.8, and 35.0 respectively. Thi...

A rapid and simple method for the determination of sulfate involving a complex formation between inorganic sulfate and the dye, toluidine blue 0, after chromatography, is presented. The method can be used for the determination of sulfate in the presence of interfering ions such as phosphate and citrate. Most of the ions have a different chromatographic migration in the solvent system employed. ...