OBJECTIVE To evaluate and update the response and survival outcomes and toxic effects in patients treated with topical nitrogen mustard (mechlorethamine hydrochloride) as primary therapy. DESIGN A single-center, retrospective cohort analysis. SETTING Academic referral center for cutaneous lymphoma. PATIENTS A total of 203 patients with mycosis fungoides (clinical stages I-III) treated wit...

BACKGROUND Bath-PUVA-photochemotherapy has become a useful alternative to oral PUVA therapy due to a number of advantages over systemic PUVA, for example, no ophthalmologic risk and nausea, and a lower cumulative UVA doses. However, its major disadvantage is the logistical requirement for bath tubs in practice and some patients feel uncomfortable to share the same bath with others. Topical psor...

Abstract This research aimed to prepare and characterize a new type of polymeric cross-linked topical hydrogel patches for the treatment wound infections. The free radical polymerization method was used by utilizing natural polymers, i.e., agarose gelatin. These polymers were chemically with monomer (acrylic acid) using ammonium persulfate as an initiator via cross-linker N , methylene bisacryl...

cystoid macular edema is a condition that involves the macula, caused by an accumulation of extracellular fluid in the macular region with secondary formation of multiple cystic spaces. this condition is provoked by a variety of pathological conditions such as intraocular inflammation, central or branch retinal vein occlusion, diabetic retinopathy and most commonly following cataract extraction...

OBJECTIVE Although topical decongestants and anesthetics are widely used in preparation for nasal endoscopy, no controlled trials have evaluated the effects of these agents on olfaction. STUDY DESIGN Randomized double-blinded controlled trial. SETTING Tertiary referral hospital. MATERIALS AND METHODS The authors recruited 72 healthy subjects and randomly assigned them to 1 of 4 groups (co...