Background: Constitutional chromosome abnormalities are among the major contributors to the genetic causes of reproductive disorders. Despite all of worldwide efforts have been made so far, the prognosis for mosaic X chromosome aberration below 30% of unemployed has yet to be established. The purpose of this study was to assess the quantity and quiddity of chromosomal aberrations that may negat...

english) The main scope of this thesis work is to compare theoretical models with experimental observations on particle transport in particular regimes of plasma operation from the Tokamak à Configuration Variable (TCV) located at CRPP–EPFL in Lausanne. We introduce the main topics in Tokamak fusion research and the challenging problems in the first Chapter. A particular attention is devoted to...

OBJECTIVE To localize susceptibility genes for alterations in brain structure associated with risk of stroke and dementia. We conducted genomewide linkage analyses for magnetic resonance imaging (MRI) measures of brain atrophy, ventricular, and subcortical white matter hyperintensity (leukoaraiosis) in 689 non-Hispanic white (673 sibling pairs; median age, 61 years) and 544 non-Hispanic black p...

In many applications, we have access to the complete dataset but are only interested in prediction of a particular region predictor variables. A standard approach is find globally best modeling method from set candidate methods. However, it perhaps rare reality that one uniformly better than others. natural for this scenario apply weighted L2 loss performance assessment reflect region-specific ...

EDS1, PAD4, and SAG101 are common regulators of plant immunity against many pathogens. EDS1 interacts with both PAD4 and SAG101 but direct interaction between PAD4 and SAG101 has not been detected, leading to the suggestion that the EDS1-PAD4 and EDS1-SAG101 complexes are distinct. We show that EDS1, PAD4, and SAG101 are present in a single complex in planta. While this complex is preferentiall...

Impaired baroreflex function is a factor responsible for poor prognosis in myocardial infarction patients. Using logistic function curves, we calculated the maximal gain of the baroreflex control of renal sympathetic nerve activity (RSNA) and heart rate in conscious Wistar-Kyoto and spontaneously hypertensive rats whose left anterior descending artery had been ligated 4 weeks earlier. We furthe...

The genomes of positive-strand RNA viruses undergo conformational shifts that complicate efforts to equate structures with function. We have initiated a detailed analysis of secondary and tertiary elements within the 3' end of Turnip crinkle virus (TCV) that are required for viral accumulation in vivo. MPGAfold, a massively parallel genetic algorithm, suggested the presence of five hairpins (H4...

Background: Typhoid vaccines are not a part of national immunization schedule in India, current survey aimed to evaluate pediatricians’ perception, recommendation patterns, and preference regarding typhoid conjugate vaccine (TCV) children adults. Methods: This was an observational, cross-sectional amongst 500 pediatricians practicing at various healthcare setups/clinics/hospitals located across...