PURPOSE Oxidative damage plays an important role in atherosclerosis development. Statin drugs have anti-oxidant properties, but the clinical value of their antioxidant properties remains unclear. In this study, our aims were: (1) to assess the anti-oxidant effects of statins in patients with coronary artery disease (CAD) using a newly developed valid measure of total oxidant and anti-oxidant ca...

This study aims to investigate the effects of Dexpanthenol (Dex), a stable alcoholic analogue D-pantothenic acid which has anti-oxidant, antiapoptotic, and antiinflammatory properties, on lipopolysaccharide (LPS)-induced lung damage via caspase-3 (cas-3) vascular cell adhesion molecule-1 (VCAM-1) levels. According experimental plan study, thirty-two Wistar Albino species rats were distributed r...

BACKGROUND Childhood obesity characterized by excessive fat in the body is one of the most serious health problems worldwide due to the social, medical, and physiological complications. Obesity and associated diseases are triggering factors for oxidative stress and inflammation. The aim of this study was to explore the possible association between childhood obesity and inflammatory and oxidativ...

background: imbalances between the oxidant-antioxidant status have been implicated in the pathogenesis of several diseases, including oral cancer. majority of oral cancer are preceded by a well-recognized group of pre-malignant lesions. however, only a small fraction of those lesions, undergo malignant transformation. hence, there is a great need to identify biological markers, which will assis...

Thyroid hormones are associated with the oxidative and antioxidative status of the organism. Depression of metabolism by hypothyroidism has been reported to decrease oxidant production and thus protect tissues against oxidant damage. The purpose of the present study was to investigate Zn and Cu levels in MMI-induced hypothyroidism and to show whether there is a connection between these trace el...

BACKGROUND AND OBJECTIVES The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in tinnitus; and to compare the results with data from healthy subjects. SUBJECTS AND METHODS A total of 114 subjects-54 patients with tinnitus and 60 healthy controls were enrolled in this study...

Five antioxidant and two oxidative stress assays were applied to serum samples of 43 healthy males. The antioxidant tests showed different inter-assay correlations. A very good correlation of 0.807 was observed between the ferric reducing ability of plasma (FRAP) and total antioxidant status (TAS) assay and also a fair correlation of 0.501 between the biological antioxidant potential (BAP) and ...

BACKGROUND F. hepatica infection is rare and mostly subclinical. Migration of juvenile forms of F. hepatica into the host's liver is accompanied by an inflammatory reaction followed by fibrosis and cirrhosis. OBJECTIVE The aim of this study was to evaluate oxidative status by using a novel automated method in patients with Fasciola hepatica. METHODS Twenty two patients with a diagnosis of F...